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具有非平衡电位的运动蛋白:其热力学与效率

Motor protein with nonequilibrium potential: Its thermodynamics and efficiency.

作者信息

Qian Hong

机构信息

Department of Applied Mathematics, University of Washington, Seattle, Washington 98195, USA.

出版信息

Phys Rev E Stat Nonlin Soft Matter Phys. 2004 Jan;69(1 Pt 1):012901. doi: 10.1103/PhysRevE.69.012901. Epub 2004 Jan 29.

Abstract

A nonequilibrium potential function is introduced for a motor protein modeled by a rectified Brownian motion. This result provides a concrete case for a class of nonequilibrium systems in steady state with dissipation which possess a potential function. The potential micro is a natural generalization of the chemical potential for isothermal chemical species and micro=const if and only if the system is in an equilibrium. The steady-state flux J proportional, variant - nabla micro, and the total heat dissipation h(d) equals a surface integral integral microJ.dS, representing the energy input. In terms of micro and h(d) the thermodynamic energy conservation in the mesoscopic stochastic system can be rigorously established and various types of motor efficiency are elucidated.

摘要

为一个由整流布朗运动建模的分子马达引入了一个非平衡势函数。这一结果为一类具有耗散的稳态非平衡系统提供了一个具体实例,这类系统拥有一个势函数。微观势是等温化学物质化学势的自然推广,当且仅当系统处于平衡态时,微观势 = 常数。稳态通量J与 -▽微观成正比,总热耗散h(d)等于一个表面积分∫微观J·dS,表示能量输入。根据微观势和h(d),可以严格建立介观随机系统中的热力学能量守恒,并阐明各种类型的分子马达效率。

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