运动训练对冠心病男性内皮功能的影响。
Effect of exercise training on endothelial function in men with coronary artery disease.
作者信息
Edwards David G, Schofield Richard S, Lennon Shannon L, Pierce Gary L, Nichols Wilmer W, Braith Randy W
机构信息
Department of Kinesiology, University of New Hampshire, Durham, New Hampshire 03824, USA.
出版信息
Am J Cardiol. 2004 Mar 1;93(5):617-20. doi: 10.1016/j.amjcard.2003.11.032.
The objective of this study was to investigate the effects of 12 weeks of standard cardiac rehabilitation on endothelial function, oxidative stress, and antioxidant defenses in patients with coronary artery disease. Twelve weeks of endurance exercise training led to an improvement in endothelial function as measured by brachial artery flow-mediated dilation (7.9% at baseline vs 11.1% at 12 weeks). Exercise training resulted in increased plasma nitrite and nitrate levels, increased plasma superoxide dismutase activity, and decreased oxidative stress.
本研究的目的是调查12周标准心脏康复对冠状动脉疾病患者内皮功能、氧化应激和抗氧化防御的影响。12周的耐力运动训练使肱动脉血流介导的扩张所测量的内皮功能得到改善（基线时为7.9%，12周时为11.1%）。运动训练导致血浆亚硝酸盐和硝酸盐水平升高、血浆超氧化物歧化酶活性增加以及氧化应激降低。
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