Hardie R M, Watson J M
Respiratory Diseases Section, PHLS Communicable Disease Surveillance Centre, London.
Epidemiol Infect. 1992 Aug;109(1):23-33.
This report reviews the literature concerning tuberculosis resulting from infection with Mycobacterium bovis in man and cattle and summarises data derived from surveillance of M. bovis in England and Wales from 1986 to 1990. Of the 228 isolates of M. bovis examined in this period, 122 (53%) were from patients aged over 60 years and are largely the result of reactivation of infection acquired prior to the institution of control measures. However, eight isolates (3.5%) were from patients aged less than 30 years. The potential sources for these presumed primary infections include the few remaining cattle infected with M. bovis or infectious human cases in the United Kingdom. However, infections acquired abroad, especially in immigrants, may account for some of these cases. Outbreaks of tuberculosis due to M. bovis continue to occur in cattle. Wild animals, particularly badgers, have been implicated as reservoirs of the infection. However, man may also prove to be an important reservoir of M. bovis for cattle as well as humans.
本报告回顾了有关人类和牛感染牛分枝杆菌所致结核病的文献,并总结了1986年至1990年英格兰和威尔士牛分枝杆菌监测数据。在此期间检测的228株牛分枝杆菌分离株中,122株(53%)来自60岁以上患者,主要是控制措施实施前获得的感染重新激活所致。然而,8株分离株(3.5%)来自30岁以下患者。这些推测的原发性感染的潜在来源包括联合王国境内少数仍感染牛分枝杆菌的牛或传染性人类病例。然而,在国外获得的感染,尤其是移民中的感染,可能占了其中一些病例。牛分枝杆菌引起的结核病疫情在牛群中仍有发生。野生动物,特别是獾,被认为是感染的储存宿主。然而,人类也可能被证明是牛分枝杆菌对牛和人类而言的重要储存宿主。