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[原发性阿米巴脑膜脑炎:一例报告]

[Primary amoebic meningoencephalitis: a case report].

作者信息

Cubero-Menéndez O, Cubero-Rego D

机构信息

Departamento de Anatomía Patológica, Hospital Pediatrico Docente William Soler, La Habana, Cuba.

出版信息

Rev Neurol. 2004;38(4):336-8.

Abstract

INTRODUCTION

Infections of the central nervous system by free-living amoeba are a rare phenomenon around the world. They present as a necrotising haemorrhagic acute meningoencephalitis, with a fatality rate close to 100% or as granulomatous amoebic encephalitis with a chronic progression.

CASE REPORT

We describe a fatal case of primary amoebic meningoencephalitis produced by Naegleria fowleri in an 8-year-old child, with a history of immersion in a freshwater reservoir 52 hours before death.

CONCLUSION

Laboratory studies carried out before death did not enable a diagnosis to be reached while the patient was alive. Diagnosis was made in the course of the post-mortem examination, where the presence of amoeba trophozoites was identified.

摘要

引言

自由生活阿米巴引起的中枢神经系统感染在全球是一种罕见现象。其表现为坏死性出血性急性脑膜脑炎,病死率接近100%,或表现为慢性进展的肉芽肿性阿米巴脑炎。

病例报告

我们描述了一例由福氏耐格里阿米巴引起的原发性阿米巴脑膜脑炎的致命病例,该8岁儿童在死亡前52小时有在淡水水库中浸泡的病史。

结论

死亡前进行的实验室检查未能在患者生前做出诊断。尸检过程中做出了诊断,发现了阿米巴滋养体的存在。

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