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来自哥斯达黎加一头奶牛的福氏耐格里阿米巴相关脑炎。

Naegleria fowleri-associated encephalitis in a cow from Costa Rica.

作者信息

Morales Juan A, Chaves Aida J, Visvesvara G S, Dubey J P

机构信息

Departamento de Patología, Escuela Medicina Veterinaria,Universidad Nacional Autonoma, Apartado 86, 3000 Heredia, Costa Rica.

出版信息

Vet Parasitol. 2006 Jun 30;139(1-3):221-3. doi: 10.1016/j.vetpar.2006.03.011. Epub 2006 Apr 25.

DOI:10.1016/j.vetpar.2006.03.011
PMID:16638625
Abstract

Species of Naegleria, Acanthamoeba, and Balamuthia are soil amoebae that can cause encephalitis in animals and humans. Of these, Naegleria fowleri is the cause of often fatal primary meningoencephalitis in humans. N. fowleri-associated encephalitis was diagnosed in a cow that was suspected to have rabies. Only formalin-fixed brain was available for diagnosis. There was severe meningoencephalitis involving all parts of the brain and numerous amoebic trophozoites were present in lesions. The amoebae reacted with N. fowleri-specific polyclonal antibodies in an indirect immunofluorescent antibody test. This is the first report of amoebic encephalitis in any host from Costa Rica.

摘要

耐格里属、棘阿米巴属和巴拉姆希阿米巴属的物种是土壤变形虫,可在动物和人类中引起脑炎。其中,福氏耐格里阿米巴是人类常致致命的原发性脑膜脑炎的病因。在一头疑似患有狂犬病的奶牛中诊断出与福氏耐格里阿米巴相关的脑炎。仅获得了用于诊断的福尔马林固定脑。存在严重的脑膜脑炎,累及脑的所有部位,病变中有大量阿米巴滋养体。在间接免疫荧光抗体试验中,这些变形虫与福氏耐格里阿米巴特异性多克隆抗体发生反应。这是哥斯达黎加任何宿主中阿米巴脑炎的首例报告。

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