Hoffman R
Universitts-Hautklinik Marburg, Marburg.
Hautarzt. 2004 Jan;55(1):89-111; quiz 110-1. doi: 10.1007/s00105-003-0673-4.
Androgenetic alopecia is the most common form of hair loss in men and women. Although the clinical manifestations are different in men and women, the pathogenetic pathways leading to this type of hair loss are similar in both sexes. In short genetically predestined hair follicles show an increased sensitivity to androgens. In recent years, much new data concerning the pathophysiology, management and therapy of androgenetic alopecia has been gathered. This article gives a critical overview of these new findings and assesses their practical relevance.
雄激素性脱发是男性和女性最常见的脱发形式。尽管男性和女性的临床表现有所不同,但导致这种脱发类型的发病机制在两性中相似。简而言之,遗传易感性毛囊对雄激素的敏感性增加。近年来,已经收集了许多关于雄激素性脱发的病理生理学、管理和治疗的新数据。本文对这些新发现进行了批判性综述,并评估了它们的实际相关性。