Roughead E E, Barratt J D, Gilbert A L
Quality Use of Medicines and Pharmacy Research Centre, School of Pharmaceutical, Molecular and Biomedical Sciences, University of South Australia, Adelaide, South Australia, Australia.
Pharmacoepidemiol Drug Saf. 2004 Feb;13(2):83-7. doi: 10.1002/pds.912.
This study characterised medication-related problems in 1000 Australian patients living in the community, and who were considered at risk of medication misadventure.
A review was undertaken of 1000 clinical case notes, developed during the delivery of medication management reviews. Patient demographics, medications used, medical conditions and medication-related problems were categorised according to established classification systems. Descriptive analyses were undertaken.
Overall, 2222 problems were identified. Ninety per cent of patients had at least one medication-related problem. One in three people were found to require additional monitoring, one in four required additional medication, one in four were using the wrong or inappropriate medication and one in five were using insufficient medication. Cardiovascular, nervous system, alimentary and respiratory medicines were most commonly implicated, accounting for 69% of the medication-related problems.
This analysis reveals the need for ongoing vigilance of, and support for, people at high risk of medication misadventure. This information is also useful for informing the design of public health or health promotion strategies aiming to reduce the prevalence of these problems.
本研究对1000名居住在社区且被认为有用药差错风险的澳大利亚患者的用药相关问题进行了特征描述。
对在提供用药管理评估期间生成的1000份临床病例记录进行了回顾。根据既定的分类系统对患者人口统计学信息、所用药物、医疗状况和用药相关问题进行了分类。进行了描述性分析。
总体而言，共识别出2222个问题。90%的患者至少有一个用药相关问题。发现三分之一的人需要额外监测，四分之一的人需要额外用药，四分之一的人使用了错误或不适当的药物，五分之一的人用药不足。心血管、神经系统、消化道和呼吸系统药物最常涉及，占用药相关问题的69%。
该分析表明需要对有用药差错高风险的人群持续保持警惕并提供支持。这些信息对于为旨在降低这些问题发生率的公共卫生或健康促进策略的设计提供参考也很有用。
