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男性和女性不孕患者对多胎妊娠的渴望。

The desire for multiple pregnancy in male and female infertility patients.

作者信息

Child Tim J, Henderson Anna Maria, Tan Seang Lin

机构信息

McGill Reproductive Center, Royal Victoria Hospital, Department of Obstetrics and Gynecology, McGill University, 687 Pine Avenue West, Montreal, Quebec H3A 1A1, Canada.

出版信息

Hum Reprod. 2004 Mar;19(3):558-61. doi: 10.1093/humrep/deh097. Epub 2004 Jan 29.

Abstract

BACKGROUND

It is apparent that many fertility patients consider multiple birth an ideal treatment outcome. We wished to evaluate the desire for multiple birth among patients, and the effect of patient demographics and recognition of the increased fetal risks of multiple pregnancy on this desire.

METHODS

This was a prospective questionnaire study completed by 801 male and female infertility patients attending a tertiary level Canadian university fertility clinic. Two logistic regression analyses were performed with desire for multiple birth with next fertility treatment and recognition of the increased fetal risks of multiple pregnancy as the dependent variables.

RESULTS

41% of patients desired a multiple birth. Increasing duration of infertility or previous assisted reproductive treatment increased, and having previous children or recognition of the increased fetal risks decreased, this desire. Patient age or sex did not affect desire for multiple birth. Previous assisted reproductive treatment was associated with increased recognition of the fetal risks of multiple pregnancy.

CONCLUSIONS

A significant proportion of fertility patients considers multiple birth an ideal treatment outcome. Recognition of the increased fetal risks of multiple pregnancy significantly reduced this desire. Patient education may play an important role in assisting physicians in the quest to reduce the contribution of assisted reproductive treatment to multiple births and their attending complications.

摘要

背景

显然,许多接受生育治疗的患者将多胎妊娠视为理想的治疗结果。我们希望评估患者对多胎妊娠的渴望,以及患者人口统计学特征和对多胎妊娠增加胎儿风险的认知对这种渴望的影响。

方法

这是一项前瞻性问卷调查研究,由801名在加拿大一所大学三级生育诊所就诊的男性和女性不孕患者完成。进行了两项逻辑回归分析,将下次生育治疗时对多胎妊娠的渴望以及对多胎妊娠增加胎儿风险的认知作为因变量。

结果

41%的患者希望多胎妊娠。不孕时间延长或既往接受辅助生殖治疗会增加这种渴望,而既往有子女或认识到多胎妊娠增加胎儿风险则会降低这种渴望。患者年龄或性别不影响对多胎妊娠的渴望。既往接受辅助生殖治疗与对多胎妊娠胎儿风险的更高认知相关。

结论

相当一部分生育患者将多胎妊娠视为理想的治疗结果。认识到多胎妊娠增加胎儿风险会显著降低这种渴望。患者教育可能在帮助医生减少辅助生殖治疗导致的多胎妊娠及其相关并发症方面发挥重要作用。

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