Weintrob Amy C, Hamilton John D, Hahn Christine, Klinzman Donna, Moyo Gustav, Zdunek Dietmar, Hess Georg, Benjamin Daniel K, Stapleton Jack T
Duke University Medical Center, Durham, North Carolina 27710, USA.
Clin Infect Dis. 2004 Mar 15;38(6):e46-8. doi: 10.1086/382079. Epub 2004 Mar 1.
To determine whether GB virus C (GBV-C) infection is associated with protection against vertical transmission of human immunodeficiency virus (HIV), we tested 186 HIV-positive pregnant women for GBV-C. Neither active nor prior GBV-C infection was associated with a lower rate of HIV acquisition among infants. Thus, GBV-C does not appear to protect against perinatal HIV acquisition.
为了确定丙型肝炎病毒(GBV-C)感染是否与预防人类免疫缺陷病毒(HIV)的垂直传播有关,我们对186名HIV阳性孕妇进行了GBV-C检测。无论是现症还是既往GBV-C感染,均与婴儿感染HIV的较低发生率无关。因此,GBV-C似乎不能预防围产期HIV感染。