Fletcher H L, Hoey E M, Orr N, Trudgett A, Fairweather I, Robinson M W
Parasite Proteomics and Therapeutics Research Group, The Queen's University of Belfast, School of Biology and Biochemistry, Medical Biology Centre, 97 Lisburn Road, Belfast BT9 7BL, UK.
Parasitology. 2004 Jan;128(Pt 1):69-72. doi: 10.1017/s003118200300427x.
Karyotyping of Fasciola hepatica samples from Britain and Ireland has identified a triploid isolate which is effectively aspermic, rendering it necessarily asexually reproducing. Considering the extensive presence of asexually reproducing diploid and triploid Fasciola in Asia it is suggested that facultative gynogenesis is widespread in this parasite. This has important implications for the population genetics and evolution of Fasciola, especially in relation to the development and spread of drug resistance, and must be considered in the mathematical modelling of this process.
对来自英国和爱尔兰的肝片吸虫样本进行的核型分析,已鉴定出一种三倍体分离株,该分离株实际上无精子,这使其必然进行无性繁殖。鉴于亚洲广泛存在无性繁殖的二倍体和三倍体肝片吸虫,有人认为兼性雌核发育在这种寄生虫中很普遍。这对肝片吸虫的群体遗传学和进化具有重要意义,特别是在耐药性的发展和传播方面,并且在这一过程的数学建模中必须予以考虑。