Poon Ian, Pintilie Melania, Potvin Mark, McGowan Tom
Department of Radiation Oncology, Toronto Sunnybrook Regional Cancer Centre, University of Toronto, Toronto, Ontario, Canada.
Can J Urol. 2004 Feb;11(1):2125-32.
Prostate cancer represents a large part of the workload for radiation oncology departments in Canada. Recent evidence suggests that conformal external beam radiotherapy improves results. The planning and treatment process for conformal patients requires a greater amount of resources that are in short supply in Ontario. An understanding of these differences is important to provide an accurate estimate of future radiation needs of the province. These differences can be quantified in a cost model that portrays the direct costs of delivering external beam radiotherapy in Ontario. With a developed cost model, a prospective direct cost comparison between standard four field external beam radiotherapy versus conformal radiotherapy in early stage prostate carcinoma was designed.
Activity based costing has been used to create a model of radiotherapy related costs for prostate cancer. A process map was developed which separated the process in five activities for conventional radiotherapy and six activities for dose escalated conformal radiotherapy. Time was recognized as the important cost driver within each activity. The time required for pre-treatment preparation (CT planning, dosimetry, simulation, and other preparatory work) and actual treatment times were collected prospectively. Treatment times were collected in 414 patients. The annual costs of capital equipment purchase costs and specialized construction of hospital space for radiotherapy equipment were amortized using a 6% discount rate plus the cost of annual maintenance. Indirect costs were not included in this cost analysis.
An activity based costing model using time as the primary cost driver reflects the additional costs of conformal over conventional external beam radiotherapy. The costs of single phase and double phase six field conformal therapy with 42 fractions delivered was 7867 Canadian dollars and 8227 Canadian dollars per patient. Four field single phase conformal therapy with 28 fractions costs 5723 Canadian dollars. The cost of conventional radiotherapy over 33 fractions was 3068 Canadian dollars. The majority of the cost differences arose from the cost of the additional time needed for treatment per day as well as the extra fractions per patient when compared to conventionally treated patients. The average treatment times per fraction for six field conformal, four field conformal and four field conventional have the median times of 22.72, 20.63 and 11.07 minutes respectively. Planning costs for conformal radiotherapy were up to three times the cost of conventional therapy.
The direct costs of dose escalated conformal external beam radiotherapy are over 2.5 times that of conventional external beam radiotherapy for early stage prostate cancer. These direct costs are a reflection of the additional capital and human resources needed to provide state-of-the-art radiation therapy in the province of Ontario. Planning for radiation oncology needs should consider the additional costs of conformal external beam radiotherapy.
前列腺癌占加拿大放射肿瘤学部门工作量的很大一部分。最近的证据表明,适形外照射放疗可改善治疗效果。适形放疗患者的计划和治疗过程需要更多资源,而安大略省这些资源短缺。了解这些差异对于准确估计该省未来的放射治疗需求非常重要。这些差异可以在一个成本模型中进行量化,该模型描绘了在安大略省提供外照射放疗的直接成本。利用一个已开发的成本模型,设计了一项针对早期前列腺癌标准四野外照射放疗与适形放疗的前瞻性直接成本比较。
基于活动的成本核算已被用于创建前列腺癌放疗相关成本的模型。绘制了一个流程图,将传统放疗过程分为五个活动,将剂量递增适形放疗过程分为六个活动。时间被视为每个活动中的重要成本驱动因素。前瞻性收集治疗前准备(CT计划、剂量测定、模拟和其他准备工作)所需时间以及实际治疗时间。收集了414例患者的治疗时间。使用6%的贴现率对放疗设备的年度资本设备购置成本和医院放疗设备专用空间建设成本进行摊销,并加上年度维护成本。本成本分析未包括间接成本。
以时间作为主要成本驱动因素的基于活动的成本核算模型反映了适形放疗相对于传统外照射放疗的额外成本。给予42次分割的单相和双相六野适形治疗的成本分别为每位患者7867加元和8227加元。给予28次分割的四野单相适形治疗成本为5723加元。33次分割的传统放疗成本为3068加元。与传统治疗患者相比,成本差异的大部分来自每天治疗所需额外时间的成本以及每位患者额外的分割次数。六野适形、四野适形和四野传统放疗每次分割的平均治疗时间中位数分别为22.72分钟、20.63分钟和11.07分钟。适形放疗的计划成本高达传统治疗成本的三倍。
对于早期前列腺癌,剂量递增适形外照射放疗的直接成本是传统外照射放疗的2.5倍以上。这些直接成本反映了在安大略省提供先进放射治疗所需的额外资本和人力资源。放射肿瘤学需求规划应考虑适形外照射放疗的额外成本。