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估算安大略省调强放疗和三维适形放疗的成本。

Estimating the costs of intensity-modulated and 3-dimensional conformal radiotherapy in Ontario.

作者信息

Yong J H E, McGowan T, Redmond-Misner R, Beca J, Warde P, Gutierrez E, Hoch J S

机构信息

St. Michael's Hospital, Toronto, ON;; Cancer Care Ontario, Toronto, ON;; Canadian Centre for Applied Research in Cancer Control, Toronto, ON;

Department of Radiation Oncology, Faculty of Medicine, University of Toronto, Toronto, ON;; The Cancer Centre Bahamas, Nassau, Bahamas;; The Cancer Centre Eastern Caribbean, St. John's, Antigua;

出版信息

Curr Oncol. 2016 Jun;23(3):e228-38. doi: 10.3747/co.23.2998. Epub 2016 Jun 9.

Abstract

BACKGROUND

Radiotherapy is a common treatment for many cancers, but up-to-date estimates of the costs of radiotherapy are lacking. In the present study, we estimated the unit costs of intensity-modulated radiotherapy (imrt) and 3-dimensional conformal radiotherapy (3D-crt) in Ontario.

METHODS

An activity-based costing model was developed to estimate the costs of imrt and 3D-crt in prostate cancer. It included the costs of equipment, staff, and supporting infrastructure. The framework was subsequently adapted to estimate the costs of radiotherapy in breast cancer and head-and-neck cancer. We also tested various scenarios by varying the program maturity and the use of volumetric modulated arc therapy (vmat) alongside imrt.

RESULTS

From the perspective of the health care system, treating prostate cancer with imrt and 3D-crt respectively cost $12,834 and $12,453 per patient. The cost of radiotherapy ranged from $5,270 to $14,155 and was sensitive to analytic perspective, radiation technique, and disease site. Cases of head-and-neck cancer were the most costly, being driven by treatment complexity and fractions per treatment. Although imrt was more costly than 3D-crt, its cost will likely decline over time as programs mature and vmat is incorporated.

CONCLUSIONS

Our costing model can be modified to estimate the costs of 3D-crt and imrt for various disease sites and settings. The results demonstrate the important role of capital costs in studies of radiotherapy cost from a health system perspective, which our model can accommodate. In addition, our study established the need for future analyses of imrt cost to consider how vmat affects time consumption.

摘要

背景

放射治疗是许多癌症的常见治疗方法,但目前缺乏对放射治疗成本的最新估计。在本研究中,我们估计了安大略省调强放射治疗(IMRT)和三维适形放射治疗(3D-CRT)的单位成本。

方法

开发了一种基于活动的成本核算模型来估计前列腺癌中IMRT和3D-CRT的成本。它包括设备、人员和支持基础设施的成本。随后调整该框架以估计乳腺癌和头颈癌的放射治疗成本。我们还通过改变项目成熟度以及在IMRT的同时使用容积调强弧形治疗(VMAT)来测试各种情况。

结果

从医疗保健系统的角度来看,分别用IMRT和3D-CRT治疗前列腺癌,每位患者的成本分别为12,834美元和12,453美元。放射治疗的成本从5,270美元到14,155美元不等,并且对分析角度、放射技术和疾病部位敏感。头颈癌病例成本最高,这是由治疗复杂性和每次治疗的分次次数驱动的。尽管IMRT比3D-CRT成本更高,但随着项目成熟和纳入VMAT,其成本可能会随着时间下降。

结论

我们的成本核算模型可以修改,以估计各种疾病部位和环境下3D-CRT和IMRT的成本。结果表明,从卫生系统角度来看,资本成本在放射治疗成本研究中具有重要作用,我们的模型可以考虑到这一点。此外,我们的研究确定了未来对IMRT成本进行分析时需要考虑VMAT如何影响时间消耗。

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