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慢性透析患者的生活质量:血液透析与腹膜透析的比较

Quality of life on chronic dialysis: comparison between haemodialysis and peritoneal dialysis.

作者信息

Wasserfallen Jean-Blaise, Halabi Georges, Saudan Patrick, Perneger Thomas, Feldman Harold I, Martin Pierre-Yves, Wauters Jean-Pierre

机构信息

University Hospital Lausanne, Switzerland.

出版信息

Nephrol Dial Transplant. 2004 Jun;19(6):1594-9. doi: 10.1093/ndt/gfh175. Epub 2004 Mar 5.

Abstract

BACKGROUND

Quality of life (QOL) assessment in patients on chronic haemodialysis (HD) or peritoneal dialysis (PD) has only rarely been carried out with the generic Euroqol-5D questionnaire.

METHODS

All chronic HD and PD patients in the 19 centres of western Switzerland were requested to fill in the validated Euroqol-5D generic QOL questionnaire, assessing health status in five dimensions and on a visual analogue scale, allowing computation of a predicted QOL value, to be compared with the value measured on the visual analogue scale.

RESULTS

Of the 558 questionnaires distributed to chronic HD patients, 455 were returned (response rate 82%). Fifty of 64 PD patients (78%) returned the questionnaire. The two groups were similar in age, gender and duration of dialysis treatment. Mean QOL was rated at 60+/-18% for HD and 61+/-19% for PD, for a mean predicted QOL value of 62+/-30 and 58+/-32% respectively. Results of the five dimensions were similar in both groups, except for a greater restriction in usual activities for PD patients (P = 0.007). The highest scores were recorded for self-care, with 71% HD and 74% PD patients reporting no limitation, and the lowest scores for usual activities, with 14% HD and 23% PD patients reporting severe limitation. Experiencing pain/discomfort (for HD and PD) or anxiety/depression (for PD) had the highest impact on QOL.

CONCLUSIONS

QOL was equally diminished in HD and PD patients. The questionnaire was well accepted and performed well. Improvement could be achievable in both groups if pain/discomfort and anxiety/depression could be more effectively treated.

摘要

背景

慢性血液透析(HD)或腹膜透析(PD)患者的生活质量(QOL)评估很少使用通用的欧洲五维健康量表(Euroqol-5D)问卷进行。

方法

要求瑞士西部19个中心的所有慢性HD和PD患者填写经过验证的Euroqol-5D通用QOL问卷,该问卷从五个维度和视觉模拟量表评估健康状况,以便计算预测的QOL值,并与视觉模拟量表上测得的值进行比较。

结果

在分发给慢性HD患者的558份问卷中,455份被退回(回复率82%)。64名PD患者中有50名(78%)退回了问卷。两组在年龄、性别和透析治疗持续时间方面相似。HD组的平均QOL评分为60±18%,PD组为61±19%,预测的平均QOL值分别为62±30%和58±32%。除了PD患者在日常活动方面受到更大限制外(P = 0.007),两组在五个维度上的结果相似。自我护理得分最高,71%的HD患者和74%的PD患者报告无限制,日常活动得分最低,14%的HD患者和23%的PD患者报告有严重限制。经历疼痛/不适(HD和PD患者)或焦虑/抑郁(PD患者)对QOL的影响最大。

结论

HD和PD患者的QOL均同样降低。该问卷被广泛接受且表现良好。如果疼痛/不适和焦虑/抑郁能够得到更有效的治疗,两组患者的QOL都有可能得到改善。

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