Ogutmen B, Yildirim A, Sever M S, Bozfakioglu S, Ataman R, Erek E, Cetin O, Emel A
Department of Nephrology, Marmara University, Istanbul, Turkey.
Transplant Proc. 2006 Mar;38(2):419-21. doi: 10.1016/j.transproceed.2006.01.016.
The purpose of this study was to compare the quality of life (QOL) in renal transplantation patients. QOL is one of the important indicators of the effects of medical treatment. In this cross-sectional study, QOL was analyzed in 302 renal transplant recipients compared with 64 hemodialysis (HD) patients, 207 (PD) peritoneal dialysis patients, and 278 normal controls (NC) matched as closely as possible to the grafted patients regarding age, gender, education, and occupation. All groups were asked to estimate their subjective QOL by responding to sociodemographic data, Turkish adapted instruments of the Nottingham Health profile (NHP), and the Short-form 36 (SF-36). Transplant recipients were significantly younger than the HD and PD patients (P < .0001). There was no statistically significant differences between normal controls and transplant patients ages. Among the three renal replacement methods, QOL in transplants was clearly better than that in HD or PD patients (P < .0001). The QOL measured by the NHP and SF-36 scale showed that the normal population was statistically significantly better than the transplant recipients (P < .0001). Transplant renal replacement therapy provides a better QOL compared with other replacement methods.
本研究的目的是比较肾移植患者的生活质量（QOL）。生活质量是医疗效果的重要指标之一。在这项横断面研究中，对302例肾移植受者的生活质量进行了分析，并与64例血液透析（HD）患者、207例腹膜透析（PD）患者以及278例在年龄、性别、教育程度和职业方面与移植患者尽可能匹配的正常对照（NC）进行了比较。所有组都被要求通过对社会人口统计学数据、土耳其语改编的诺丁汉健康概况（NHP）量表以及简短健康调查问卷（SF - 36）做出回应来评估他们的主观生活质量。移植受者明显比血液透析和腹膜透析患者年轻（P < .0001）。正常对照组和移植患者的年龄之间没有统计学上的显著差异。在三种肾脏替代方法中，移植患者的生活质量明显优于血液透析或腹膜透析患者（P < .0001）。通过NHP和SF - 36量表测量的生活质量显示，正常人群在统计学上明显优于移植受者（P < .0001）。与其他替代方法相比，移植肾替代疗法能提供更好的生活质量。
