Danesch Ulrich C
University of Heidelberg, Germany.
Altern Med Rev. 2004 Mar;9(1):54-62.
The efficacy and tolerability of a butterbur root extract (Petadolex) for the treatment of asthma was analyzed in a prospective, non-randomized, open trial. Subjects included 64 adults and 16 children/adolescents treated for two months with the extract, followed by two months during which the intake of the extract was optional. Concomitant asthma medication was permitted. The number, duration, and severity of asthma attacks decreased, while peak flow, forced expiratory volume (FEV1), and all measured symptoms improved during therapy. In addition, more than 40 percent of patients using asthma medications at baseline reduced intake of these medications by the end of the study. This study suggests the Petasites hybridus extract Petadolex is an effective and safe therapy for the treatment of asthma.
在一项前瞻性、非随机、开放试验中，分析了一种款冬根提取物（Petadolex）治疗哮喘的疗效和耐受性。受试者包括64名成人和16名儿童/青少年，用该提取物治疗两个月，随后两个月提取物的摄入为可选。允许使用哮喘伴随药物。哮喘发作的次数、持续时间和严重程度减少，同时在治疗期间峰值流量、用力呼气量（FEV1）和所有测量的症状均得到改善。此外，超过40%在基线时使用哮喘药物的患者在研究结束时减少了这些药物的摄入量。这项研究表明，款冬提取物Petadolex是一种治疗哮喘的有效且安全的疗法。
