Tiplady Brian, Franklin Nicola, Scholey Andrew
AstraZeneca UK Clinical Research Group, Edinburgh, UK.
Br J Psychol. 2004 Feb;95(Pt 1):105-18. doi: 10.1348/000712604322779497.
Ethanol impairs cognitive and psychomotor performance, although the precise reasons for this remain unclear. We investigated the effect of ethanol on individuals' judgment of their performance. Eighteen healthy volunteers (19-22 years) received a high dose of ethanol (0.8 g/kg for males and 0.7 g/kg, for females), a medium dose (75% of the high dose) and a placebo in counterbalanced order on three study days. A general knowledge (GK) test was administered on a pen computer 75 min after the drink. An adaptive algorithm adjusted the difficulty of questions so that scores were similar on all three study days. Volunteers then rated how well they believed they had performed the GK task using a visual analogue scale. A battery of other performance tests and mood ratings was also completed both before and after the GK test. These showed the expected effects of ethanol. There were no significant differences in scores on the GK test between treatment sessions. There was a highly significant dose-dependent increase with ethanol on volunteers' ratings of their performance on this test. These findings suggest that ethanol leads to an overoptimistic assessment of ability which may contribute to ethanol's impairment of performance.
乙醇会损害认知和精神运动表现,尽管其确切原因尚不清楚。我们研究了乙醇对个体对自身表现判断的影响。18名健康志愿者(19 - 22岁)在三个研究日以平衡顺序接受高剂量乙醇(男性0.8克/千克,女性0.7克/千克)、中剂量(高剂量的75%)和安慰剂。饮酒75分钟后,在笔式电脑上进行常识(GK)测试。一种自适应算法调整问题难度,以便在所有三个研究日的分数相似。志愿者随后使用视觉模拟量表对他们认为自己在GK任务中的表现进行评分。在GK测试前后还完成了一系列其他性能测试和情绪评分。这些显示了乙醇的预期效果。各治疗阶段之间GK测试的分数没有显著差异。乙醇使志愿者对该测试表现的评分呈高度显著的剂量依赖性增加。这些发现表明,乙醇会导致对能力的过度乐观评估,这可能导致乙醇对表现的损害。