Psychology Department, Faculty of Health and Life Sciences, University of the West of England, Frenchay Campus, Coldharbour Lane, Bristol, BS16 1QY, UK.
Psychopharmacology (Berl). 2012 Aug;222(3):519-32. doi: 10.1007/s00213-012-2677-1. Epub 2012 Mar 29.
This study investigated the coadministration of an energy drink with alcohol to study the effects on subjective intoxication and objective performance.
This study aims to evaluate the objective and subjective effects of alcohol versus placebo at two alcohol doses, alone and in combination with an energy drink, in a balanced order, placebo-controlled, double-blind design.
Two groups of ten healthy volunteers, mean (SD) age of 24 (6.5), participated in the study. One group consumed energy drink containing 80 mg of caffeine and the other consumed a placebo drink, with both receiving two alcohol doses (0.046 and 0.087% breathalyser alcohol concentration). Tests included breath alcohol assessment, objective measures of performance (reaction time, word memory and Stroop task) and subjective visual analogue mood scales.
Participants showed significantly impaired reaction time and memory after alcohol compared to the no alcohol condition and had poorer memory after the higher alcohol dose. Stroop performance was improved with the energy drink plus alcohol combination compared to the placebo drink plus alcohol combination. Participants felt significant subjective dose-related impairment after alcohol compared to no alcohol. Neither breath alcohol concentration nor the subjective measures showed a significant difference between the energy drink and the placebo energy drink when combined with alcohol.
Subjective effects reflected awareness of alcohol intoxication and sensitivity to increasing alcohol dose. There were no overall significant group differences for subjective measures between energy drink and placebo groups in the presence of alcohol and no evidence that the energy drink masked the subjective effects of alcohol at either dose.
本研究旨在调查能量饮料与酒精同时摄入对主观醉酒和客观表现的影响。
能量饮料在年轻人中越来越受欢迎，与酒精一起摄入的情况也越来越多。然而，关于能量饮料与酒精联合摄入对醉酒和表现的影响的研究结果相互矛盾。
本研究采用平衡、安慰剂对照、双盲设计，纳入了两组各 10 名健康志愿者（平均年龄 24 岁±6.5 岁）。一组饮用含有 80mg 咖啡因的能量饮料，另一组饮用安慰剂饮料，同时接受两种酒精剂量（呼气酒精浓度为 0.046%和 0.087%）。测试包括呼气酒精评估、客观表现测试（反应时间、单词记忆和 Stroop 任务）和主观视觉模拟情绪量表。
与无酒精相比，参与者在摄入酒精后反应时间和记忆力明显下降，且在高酒精剂量后记忆力更差。与安慰剂饮料加酒精组相比，能量饮料加酒精组的 Stroop 表现有所改善。与无酒精相比，参与者在摄入酒精后主观感觉明显受损，且与酒精剂量相关。无论是否与酒精同时摄入，呼气酒精浓度或主观测量结果均未显示能量饮料与安慰剂能量饮料之间存在显著差异。
主观效应反映了对醉酒的意识和对酒精剂量增加的敏感性。在酒精存在的情况下，能量饮料组和安慰剂组之间的主观测量值没有总体显著的组间差异，并且没有证据表明能量饮料在任何剂量下都能掩盖酒精的主观效应。
