发作性偏头痛患者头痛慢性化的发生率及预测因素

Incidence and predictors for chronicity of headache in patients with episodic migraine.

作者信息

Katsarava Z, Schneeweiss S, Kurth T, Kroener U, Fritsche G, Eikermann A, Diener H-C, Limmroth V

机构信息

Department of Neurology, University Hospital Essen, Germany.

出版信息

Neurology. 2004 Mar 9;62(5):788-90. doi: 10.1212/01.wnl.0000113747.18760.d2.

DOI:10.1212/01.wnl.0000113747.18760.d2

PMID:15007133

Abstract

The authors followed 532 consecutive patients with episodic migraine (<15 days/month) for 1 year. Sixty-four patients (14%) developed chronic headache (>/=15 days/month). The odds ratios for developing CH were 20.1 (95% CI 5.7 to 71.5) comparing patients with a "critical" (10 to 14 days/month) vs "low" (0 to 4 days/month) and 6.2 (95% CI 1.7 to 26.6) in patients with an "intermediate" (6 to 9 days/month) vs "low" headache frequency and 19.4 (95% CI 8.7 to 43.2) comparing patients with and without medication overuse.

摘要

作者对532例连续性发作性偏头痛（每月<15天）患者进行了为期1年的随访。64例患者（14%）发展为慢性头痛（每月≥15天）。与“低”（每月0至4天）发作频率的患者相比，“临界”（每月10至14天）发作频率的患者发生慢性头痛的比值比为20.1（95%可信区间5.7至71.5）；与“低”发作频率的患者相比，“中等”（每月6至9天）发作频率的患者发生慢性头痛的比值比为6.2（95%可信区间1.7至26.6）；有药物过度使用和无药物过度使用的患者相比，发生慢性头痛的比值比为19.4（95%可信区间8.7至43.2）。