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为何我们在亲属活体肾移植中持续选用左侧供肾:右侧腹腔镜供肾切除术的初步经验及与左侧肾切除术的比较

Why we consistently use the left donor kidney in living related transplantation: initial experience of right laparoscopic donor nephrectomy and comparison with left nephrectomy.

作者信息

Liu K-L, Chiang Y-J, Wu C-T, Lai W-J, Wang H-H, Chu S-H

机构信息

Division of Urology, Department of Surgery, Chang Gung Memorial Hospital, Chang Gung University, 5 Fu-Hsing Street, Kewishan Hsiang, Taoyuan 333, Taiwan.

出版信息

Transplant Proc. 2006 Sep;38(7):1977-9. doi: 10.1016/j.transproceed.2006.06.023.

Abstract

OBJECTIVES

Laparoscopic donor nephrectomy has become the method of choice for removal of living donor kidneys. However, the majority of laparoscopic donor nephrectomy cases have been limited to the left side owing to technical difficulties and renal vessel length. This study described the technique and compared donor outcomes and graft function of right and left laparoscopic donor nephrectomy.

MATERIALS AND METHODS

Among 25 patients, 6 consecutive donors underwent right laparoscopic donor nephrectomy from March 2002 to January 2005. They were compared to 19 patients with left laparoscopic donor nephrectomy. We compared operative times, warm ischemia times, serial creatinines, creatinine clearances, complications, and graft function.

RESULTS

There was no significant difference in any metric. The operative times (303 min. vs 274 min., P > .05) and warm ischemia times (133 s vs 186 s, P > .05) were similar between right and left laparoscopic donor nephrectomy procedures. In left laparoscopic donor nephrectomy, 3 patients had transient brachial plexus neuropathies. No major complication occurred among patients undergoing right laparoscopic donor nephrectomy. This study demonstrated that both donor and recipient outcomes are similar for right and left laparoscopic donor nephrectomy.

CONCLUSIONS

Consistent use of the left kidney has not affected clinical outcomes. With hand-assisted laparoscopy, the right laparoscopic donor nephrectomy is safe, providing excellent graft function.

摘要

目的

腹腔镜供肾切除术已成为活体供肾切除的首选方法。然而,由于技术难度和肾血管长度的原因,大多数腹腔镜供肾切除术病例仅限于左侧。本研究描述了该技术,并比较了左右侧腹腔镜供肾切除术的供体结局和移植肾功能。

材料与方法

在25例患者中,2002年3月至2005年1月期间连续有6例供体接受了右侧腹腔镜供肾切除术。将他们与19例接受左侧腹腔镜供肾切除术的患者进行比较。我们比较了手术时间、热缺血时间、系列肌酐、肌酐清除率、并发症和移植肾功能。

结果

各项指标均无显著差异。左右侧腹腔镜供肾切除术的手术时间(303分钟对274分钟,P>.05)和热缺血时间(133秒对186秒,P>.05)相似。在左侧腹腔镜供肾切除术中,3例患者出现短暂性臂丛神经病变。接受右侧腹腔镜供肾切除术的患者未发生重大并发症。本研究表明,左右侧腹腔镜供肾切除术的供体和受体结局相似。

结论

持续使用左肾并未影响临床结局。通过手辅助腹腔镜,右侧腹腔镜供肾切除术是安全的,可提供良好的移植肾功能。

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