Kales Helen C, Blow Frederic C, Welsh Deborah E, Mellow Alan M
Psychiatry Service (116A), VA Ann Arbor Healthcare System, 2215 Fuller Road, Ann Arbor, MI, 48105, USA.
J Geriatr Psychiatry Neurol. 2004 Mar;17(1):25-31. doi: 10.1177/0891988703261998.
The use of herbal products and other "natural" supplements among the US population is on the rise. Limited data suggest that such use among the elderly may correlate with higher education levels as well as psychiatric symptoms. The authors examined herbal/supplement use among elderly veterans with depression and/or dementia (n = 82) and their primarily elderly caregivers (n = 56). Eighteen percent of subjects and 16% of caregivers used herbals/supplements. Seventy-five percent of subjects who used these products during the study period were also taking potentially interacting medications. Given the prior association of herbal/supplement use with higher education levels, a surprising number of elderly veterans with depression and/or dementia (the majority of whom had high school or less education) used these products. As evidenced by missing documentation in many physician notes, subjects may not have discussed their usage of herbals/supplements with their physicians. In light of the possibility of potentially harmful drug interactions, physicians who treat elderly patients should regularly inquire about the use of these products.
美国人群中使用草药产品和其他“天然”补充剂的情况正在增加。有限的数据表明,老年人中的这种使用情况可能与较高的教育水平以及精神症状相关。作者研究了患有抑郁症和/或痴呆症的老年退伍军人(n = 82)及其主要为老年人的护理人员(n = 56)中草药/补充剂的使用情况。18%的受试者和16%的护理人员使用草药/补充剂。在研究期间使用这些产品的受试者中有75%也在服用可能相互作用的药物。鉴于之前草药/补充剂的使用与较高教育水平之间的关联,令人惊讶的是,许多患有抑郁症和/或痴呆症的老年退伍军人(其中大多数人受教育程度为高中或更低)使用了这些产品。正如许多医生记录中缺少相关文件所证明的那样,受试者可能没有与他们的医生讨论过他们使用草药/补充剂的情况。鉴于存在潜在有害药物相互作用的可能性,治疗老年患者的医生应定期询问这些产品的使用情况。