• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Immunomodulatory and neuroprotective effects of inosine.

作者信息

Haskó György, Sitkovsky Michail V, Szabó Csaba

机构信息

Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 10/11N311, 10 Center Drive, Bethesda, MD 20892-1892, USA.

出版信息

Trends Pharmacol Sci. 2004 Mar;25(3):152-7. doi: 10.1016/j.tips.2004.01.006.

DOI:10.1016/j.tips.2004.01.006
PMID:15019271
Abstract
摘要

相似文献

1
Immunomodulatory and neuroprotective effects of inosine.肌苷的免疫调节和神经保护作用。
Trends Pharmacol Sci. 2004 Mar;25(3):152-7. doi: 10.1016/j.tips.2004.01.006.
2
Effects of inosine on neuronal apoptosis and the expression of cytochrome C mRNA following hypoxic-ischemic brain damage in neonatal rats.肌苷对新生大鼠缺氧缺血性脑损伤后神经元凋亡及细胞色素C mRNA表达的影响。
Zhongguo Dang Dai Er Ke Za Zhi. 2006 Aug;8(4):266-71.
3
Inosine released after hypoxia activates hepatic glucose liberation through A3 adenosine receptors.缺氧后释放的肌苷通过A3腺苷受体激活肝脏葡萄糖释放。
Am J Physiol Endocrinol Metab. 2006 May;290(5):E940-51. doi: 10.1152/ajpendo.00173.2005. Epub 2005 Dec 13.
4
Inosine : a naturally occurring cardiotonic agent.肌苷:一种天然存在的强心剂。
J Pharmacol. 1983;14 Suppl 3:47-71.
5
Protective effect of inosin in protracted artificial circulation in experiment.肌苷在实验性长时间人工循环中的保护作用。
Cor Vasa. 1981;23(5):381-8.
6
[Energizing and antihypoxic effects of energostime].[能量时的赋能及抗缺氧作用]
Biull Eksp Biol Med. 1997 Jun;123(6):659-62.
7
Effects of inosine on response to in vitro hypoxia in absence of substrate on bladder dysfunction in adult rats.
Urology. 2009 Mar;73(3):661-4. doi: 10.1016/j.urology.2008.10.024. Epub 2008 Dec 21.
8
Boosting endogenous neuroprotection in multiple sclerosis: the ASsociation of Inosine and Interferon beta in relapsing- remitting Multiple Sclerosis (ASIIMS) trial.多发性硬化症中的内源性神经保护增强:肌苷和干扰素β在复发缓解型多发性硬化症(ASIIMS)试验中的关联。
Mult Scler. 2010 Apr;16(4):455-62. doi: 10.1177/1352458509360547. Epub 2010 Mar 3.
9
Purine nucleoside-mediated protection of chemical hypoxia-induced neuronal injuries involves p42/44 MAPK activation.嘌呤核苷介导的对化学性缺氧诱导的神经元损伤的保护作用涉及p42/44丝裂原活化蛋白激酶的激活。
Neurochem Int. 2005 Jun;46(7):513-21. doi: 10.1016/j.neuint.2005.02.003.
10
Inosine reduces ischemic brain injury in rats.肌苷可减轻大鼠的缺血性脑损伤。
Stroke. 2005 Mar;36(3):654-9. doi: 10.1161/01.STR.0000155747.15679.04. Epub 2005 Feb 3.

引用本文的文献

1
Classically activated macrophages undergo functionally significant nucleotide metabolism remodelling driven by nitric oxide.经典激活的巨噬细胞经历由一氧化氮驱动的具有功能意义的核苷酸代谢重塑。
Nat Metab. 2025 Aug 4. doi: 10.1038/s42255-025-01337-3.
2
Generation of Immune Modulating Small Metabolites-Metabokines-By Adult Schistosomes.成年血吸虫产生免疫调节性小代谢物——代谢因子
Pathogens. 2025 May 24;14(6):526. doi: 10.3390/pathogens14060526.
3
Metabolomic analysis of bioactive compounds in dill ( L.) extracts.莳萝提取物中生物活性化合物的代谢组学分析。
PeerJ. 2025 Jun 10;13:e19567. doi: 10.7717/peerj.19567. eCollection 2025.
4
Inosine Treatment Attenuates White Matter Injury in Neonatal Rats Exposed to Maternal Inflammation.肌苷治疗可减轻暴露于母体炎症的新生大鼠的白质损伤。
Neurochem Res. 2025 May 30;50(3):176. doi: 10.1007/s11064-025-04429-4.
5
Gut microbiota and relevant metabolites analysis in perianal abscess of infants.婴儿肛周脓肿的肠道微生物群及相关代谢产物分析
BMC Microbiol. 2025 May 28;25(1):333. doi: 10.1186/s12866-025-04020-5.
6
Extracellular Inosine Induces Anergy in B Cells to Alleviate Autoimmune Hepatitis.细胞外肌苷诱导B细胞无能以减轻自身免疫性肝炎。
Cell Mol Gastroenterol Hepatol. 2025 May 21;19(10):101539. doi: 10.1016/j.jcmgh.2025.101539.
7
Multiomics analysis unveils an inosine-sensitive DNA damage response in neurogenic bladder after spinal cord injury.多组学分析揭示了脊髓损伤后神经源性膀胱中对肌苷敏感的DNA损伤反应。
JCI Insight. 2025 May 8;10(12). doi: 10.1172/jci.insight.180275. eCollection 2025 Jun 23.
8
Effects of high-dose glucose oxidase on broiler growth performance, antioxidant function, and intestinal microbiota in broilers.高剂量葡萄糖氧化酶对肉鸡生长性能、抗氧化功能及肠道微生物群的影响
Front Microbiol. 2024 Oct 28;15:1439481. doi: 10.3389/fmicb.2024.1439481. eCollection 2024.
9
Inosine Improves Functional Recovery and Cell Morphology Following Compressive Spinal Cord Injury in Mice.肌苷可改善小鼠脊髓压迫性损伤后的功能恢复和细胞形态。
Neurotrauma Rep. 2024 Oct 2;5(1):957-968. doi: 10.1089/neur.2024.0081. eCollection 2024.
10
Mesenchymal Stem/Stromal Cells Derived from Dental Tissues Mediate the Immunoregulation of T Cells through the Purinergic Pathway.牙髓组织来源的间充质干细胞通过嘌呤能途径介导 T 细胞的免疫调节。
Int J Mol Sci. 2024 Sep 4;25(17):9578. doi: 10.3390/ijms25179578.