一名6岁男孩肾上腺神经节瘤发生恶性周围神经鞘膜瘤。

Malignant peripheral nerve sheath tumor arising from an adrenal ganglioneuroma in a 6-year-old boy.

作者信息

de Chadarévian Jean-Pierre, MaePascasio Judy, Halligan Gregory E, Katz Douglas A, Locono Joseph A, Kimmel Stephen, Katsetos Christos D

机构信息

Department of Pathology and Laboratory Medicine, St. Christopher's Hospital for Children, and Drexel University College of Medicine, Philadelphia, PA 19134, USA.

出版信息

Pediatr Dev Pathol. 2004 May-Jun;7(3):277-84. doi: 10.1007/s10024-004-8084-9. Epub 2004 Mar 17.

DOI:10.1007/s10024-004-8084-9

PMID:15022069

Abstract

This report describes the youngest patient to develop a malignant peripheral nerve sheath tumor arising from a ganglioneuroma (MPNST ex Ganglioneuroma). The patient, a 6-year-old boy, was never irradiated and had no history or stigmata of neurofibromatosis. The report also includes a review of the previously published related cases, and an analysis of the immunohistochemistry and electron microscopy data available to date on the subject.

摘要

本报告描述了一名最年轻的发生于神经节神经瘤的恶性外周神经鞘瘤（源于神经节神经瘤的恶性外周神经鞘瘤）患者。该患者为一名6岁男孩，从未接受过放疗，也没有神经纤维瘤病的病史或体征。本报告还包括对既往发表的相关病例的综述，以及对目前该主题可用的免疫组织化学和电子显微镜数据的分析。