Kubo Isao, Xu Yunlong, Shimizu Kuniyoshi
Department of Environmental Science, Policy and Management, University of California, Berkeley, CA 94720-3112, USA.
Phytother Res. 2004 Feb;18(2):180-3. doi: 10.1002/ptr.1421.
Biological activities of ent-kaurene diterpenoids, rosthornins A-D, isolated from the ether extract of the dried leaves of Rabdosia rosthornii (Diels) Hara (Labiatae) were tested. They exhibited antibacterial activity specifically against Gram-positive bacteria, among which Propionibacterium acnes was noted to be the most susceptible.