Scutellari P N, Orzincolo C, Princivalle M, Franceschini F
Istituto di Radiologia, Università, Ferrara.
Radiol Med. 1992 Jun;83(6):729-36.
DISH is a common systemic skeletal disease, probably of dysmetabolic and/or degenerative origin, yet of unknown etiology. It is observed in middle-aged or elderly patients of both sexes, and is characterized by ossification of the anterior longitudinal ligament on the antero-lateral aspect of the spine, and by ossifying enthesopathy, in both the central and the peripheral skeleton. Diagnosis is solely based on radiographic abnormalities, according to the so-called Resnick criteria. In the present study, the spines of 915 patients (414 males, 501 females, mean age: 65 years) were considered, and the peripheral entheses (heel, patella and elbow) of 494 of them (234 males and 260 females). The incidence of DISH was 14.09% (129 cases): 17.6% in males (73 cases) and 11.7% in females (56 cases). DISH strikes in the VI and VII decades of life most. The most affected sites of the spine were: the dorsal portion (100%), especially in the D7-D11 segment (93%); the lumbar spine in L1-L3 (81%), and the cervical spine, in the C5-C7 segment (69%). Peripheral areas of involvement were: pelvis (90%), heel (76%), elbow (46%) and knee (29%). The symptoms of DISH must be promptly detected: the disease is not asymptomatic, but presents with pain and stiffness in the spine, recurrent tendinitis and bursitis, and myelopathy.
弥漫性特发性骨肥厚（DISH）是一种常见的全身性骨骼疾病，可能起源于代谢紊乱和/或退行性变，但其病因不明。在中年或老年男女患者中均可观察到，其特征是脊柱前外侧的前纵韧带骨化，以及在中轴和外周骨骼中出现骨化性附着点病。诊断完全基于影像学异常，依据所谓的雷斯尼克标准。在本研究中，纳入了915例患者的脊柱（男性414例，女性501例，平均年龄：65岁），其中494例患者（男性234例，女性260例）的外周附着点（足跟、髌骨和肘部）也被纳入研究。DISH的发病率为14.09%（129例）：男性为17.6%（73例），女性为11.7%（56例）。DISH最常发生在60和70岁年龄段。脊柱最常受累的部位是：背部（100%），尤其是D7 - D11节段（93%）；腰椎L1 - L3节段（81%），以及颈椎C5 - C7节段（69%）。外周受累部位包括：骨盆（90%）、足跟（76%）、肘部（46%）和膝部（29%）。必须及时发现DISH的症状：该疾病并非无症状，而是表现为脊柱疼痛和僵硬、复发性肌腱炎和滑囊炎以及脊髓病。
