Rinaggio Joseph, Duffey Dianne, McGuff H Stan
Department of Diagnostic Sciences, University of Medicine and Dentistry of New Jersey-New Jersey Dental School, Newark 07103-2400, USA.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2004 Mar;97(3):369-75. doi: 10.1016/j.tripleo.2003.09.015.
Dedifferentiated chondrosarcoma is an uncommon malignant cartilaginous neoplasm of bone characterized by the presence of a malignant spindle cell neoplasm associated with a low- or medium-grade chondrosarcoma. Origin of this tumor in the cartilagenous framework of the larynx is very rare. A 60-year-old male with a 2-year history of hoarseness and dyspnea was examined while presenting in acute airway distress. Direct laryngoscopy revealed a mass of the right side of the larynx. Histopathologic examination revealed a malignant cartilaginous tumor with a malignant spindle cell component. We report a case of dedifferentiated chondrosarcoma arising in the thyroid cartilage. This, to our knowledge, is the eleventh fully documented case of this neoplasm arising in the larynx.
去分化软骨肉瘤是一种罕见的骨恶性软骨肿瘤，其特征是存在与低级别或中级别软骨肉瘤相关的恶性梭形细胞瘤。该肿瘤起源于喉软骨结构非常罕见。一名有2年声音嘶哑和呼吸困难病史的60岁男性在急性气道窘迫时接受检查。直接喉镜检查发现喉部右侧有一个肿块。组织病理学检查显示为一个具有恶性梭形细胞成分的恶性软骨肿瘤。我们报告一例起源于甲状软骨的去分化软骨肉瘤病例。据我们所知，这是文献充分记载的第11例起源于喉部的该肿瘤病例。
