Kumar Arun
Department of Clinical Biochemistry, Nepal Medical College, Kathmandu, Nepal.
Nepal Med Coll J. 2003 Dec;5(2):102-4.
The study was carried out to assess whether Urinary Tract Infection (UTI) is a predisposing factor for Renal Stones (RS) formation. A total of 836 subjects (males 300; females 536) attending Surgery Out Patient Department (OPD) of which were either diagnosed of UTI or had been detected of RS for a period of two years from January 2001 to December 2002 were included. Of the 836, 240 had UTI and 596 were free from UTI. The prevalence of RS was higher without UTI (44.4%) than those with UTI (27.8%) in males. In case of females the result showed (17.6%) and (5.1%) in cases with and without UTI. Chi square test revealed statistically significant difference in the proportion of prevalence between subjects with and without UTI with (p < 0.01) in males and (p < 0.001) in females. Males had higher incidence of RS than females with a prevalence of (p < 0.0001). The higher occurrence of RS was observed in age group between 21-40 years for both genders.
开展该研究以评估尿路感染(UTI)是否为肾结石(RS)形成的诱发因素。纳入了2001年1月至2002年12月期间在外科门诊就诊的836名受试者(男性300名;女性536名),这些受试者要么被诊断为UTI,要么被检测出患有RS,为期两年。在这836名受试者中,240名患有UTI,596名无UTI。男性中无UTI者的RS患病率(44.4%)高于患有UTI者(27.8%)。女性方面,有UTI和无UTI的病例结果分别为(17.6%)和(5.1%)。卡方检验显示,男性中患有和未患有UTI的受试者患病率比例存在统计学显著差异(p < 0.01),女性中该差异更为显著(p < 0.001)。男性的RS发病率高于女性,患病率差异具有统计学意义(p < 0.0001)。两个性别在21 - 40岁年龄组中均观察到较高的RS发生率。