Saini Santosh, Goel Nidhi, Sharma Madhu, Arora B, Garg Nidhi
Department of Microbiology, Postgraduate Institute of Medical Sciences, Rohtak, Haryana.
Indian J Pathol Microbiol. 2003 Jul;46(3):515-6.
The present study was conducted on 25 cases of preterm, premature rupture of membranes and 25 patients preterm with intact membranes, between 28-36 weeks of gestation, admitted in the maternity ward of Obstetrics and Gynecology, PGIMS, Rohtak. The sensitivity and specificity of CRP determination was found to be 80% each as an early predictor of subclinical chorioamnionitis. TLC had a low sensitivity of 20% and specificity of 60% in detecting histopathological chorioamnionitis. So CRP estimation is a reliable marker for detection of early choriamnionitis, at the same time, it is quite affordable and reasonably simple.
本研究针对25例胎膜早破的早产患者和25例胎膜完整的早产患者开展，这些患者孕周在28 - 36周之间，收治于罗塔克PGIMS妇产科的产科病房。作为亚临床绒毛膜羊膜炎的早期预测指标，CRP测定的敏感性和特异性均为80%。在检测组织病理学绒毛膜羊膜炎方面，白细胞计数（TLC）的敏感性低至20%，特异性为60%。因此，CRP测定是检测早期绒毛膜羊膜炎的可靠标志物，同时，它价格实惠且操作相当简便。
