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白细胞介素8(IL-8)——一种通用生物标志物?

Interleukin 8 (IL-8) - a universal biomarker?

作者信息

Shahzad Aamir, Knapp Martin, Lang Irene, Köhler Gottfried

机构信息

Max F, Perutz Laboratories, Department of Structural Biology and Biomolecular Chemistry, University of Vienna, Vienna, Austria.

出版信息

Int Arch Med. 2010 Jun 15;3:11. doi: 10.1186/1755-7682-3-11.

Abstract

Many clinical conditions including various types of cancers are complex and generally require invasive, laborious, expensive and time-consuming investigations for their diagnosis, treatment and follow-up. There is therefore a general need for exploring non-invasive markers in clinical medicine. Interleukin 8 (IL-8) is currently being applied in various subspecialties of medicine either for the purpose of rapid diagnosis or as a predictor of prognosis. Nevertheless, there is need for large-scale studies to substantiate accuracy and outcome. This article will summarize current evidence suggesting that Interleukin 8 (IL-8) may serve as a useful biomarker.

摘要

许多临床病症,包括各种类型的癌症,都很复杂,通常需要进行侵入性、费力、昂贵且耗时的检查来进行诊断、治疗和随访。因此,临床医学普遍需要探索非侵入性标志物。白细胞介素8(IL-8)目前正在医学的各个亚专业中应用,目的要么是快速诊断,要么是作为预后的预测指标。然而,需要大规模研究来证实其准确性和结果。本文将总结当前的证据,表明白细胞介素8(IL-8)可能是一种有用的生物标志物。

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