Bliwise Donald L, Irbe Dainis, Schulman David A
Sleep Disorders Center, Emory University Medical School, Atlanta, Georgia 30329, USA.
Sleep Breath. 2004 Mar;8(1):43-7. doi: 10.1007/s11325-004-0043-1.
We report a 38-year-old man with obstructive sleep apnea whose sleep-disordered breathing was substantially reduced by sleep in the supine, "knees-up" position, relative to his sleep in the customary supine, "knees-down" position. No obvious anatomic or pathophysiologic alterations explained this phenomenon. The effect was reproducible in the patient 4 years later. Potential mechanisms underlying such improvement, including alterations in upper airway/lung volume dependence and venous supply to upper airway vasculature, are discussed. This manipulation could be an important adjunctive treatment for a subset of obstructive sleep apnea patients demonstrating such an effect.
我们报告了一名38岁患有阻塞性睡眠呼吸暂停的男性,相对于其习惯的仰卧位“屈膝向下”睡眠姿势,仰卧位“屈膝向上”睡眠姿势时,他的睡眠呼吸障碍显著减轻。没有明显的解剖学或病理生理学改变能解释这一现象。4年后该患者身上再现了这种效果。本文讨论了这种改善的潜在机制,包括上气道/肺容量依赖性改变以及上气道血管系统的静脉供应改变。对于表现出这种效果的一部分阻塞性睡眠呼吸暂停患者而言,这种睡眠姿势调整可能是一种重要的辅助治疗方法。