Greer Sophia A, Straight Laura-Beth, Schulman David A, Bliwise Donald L
Program in Sleep, Aging and Chronobiology, Emory University Medical School, Wesley Woods Center, 1841 Clifton Road, Atlanta, GA, 30329, USA.
Sleep Breath. 2006 Jun;10(2):98-101. doi: 10.1007/s11325-005-0051-9.
We previously reported a case of a middle-aged man whose obstructive sleep apnea (OSA) was virtually eliminated when he slept in the supine "knees up" position. In this study, we attempt to replicate this phenomenon in a group of volunteers with previously diagnosed OSA. Results indicated no significant improvement in OSA when sleeping supine knees up. Examination of distribution of within subjects' change [calculated as Respiratory Disturbance Index (RDI) in the "knees down" position vs RDI in the knees up position] indicated a trend for improvement in the latter (p=0.12, two-tailed probability). These results suggest that knee position is unlikely to be a robust intervention for OSA though they allow for the possibility that some patients may have a moderation of their condition by such a manipulation.
我们之前报道过一例中年男性，当他以仰卧“屈膝”姿势睡觉时，其阻塞性睡眠呼吸暂停（OSA）几乎消除。在本研究中，我们试图在一组先前被诊断为OSA的志愿者中重现这一现象。结果表明，仰卧屈膝睡眠时OSA无显著改善。对受试者内变化分布的检查[计算为“屈膝向下”姿势下的呼吸紊乱指数（RDI）与屈膝向上姿势下的RDI]表明，后者有改善趋势（p = 0.12，双侧概率）。这些结果表明，膝盖位置不太可能是治疗OSA的有效干预措施，尽管它们允许这样一种可能性，即一些患者可能通过这种操作使病情得到缓解。
