Fasola F A, Okunade M A, Abjah U M A
Department of Haematology, University College Hospital, Ibadan, Nigeria.
Afr J Med Med Sci. 2002 Dec;31(4):337-9.
The need for platelet transfusion has increased at the University College Hospital (U.C.H.) Ibadan, Nigeria because of improved patient care and use of intensive therapeutic regimen associated with bone marrow aplasia. Therefore there is a need to assess the quality of the platelet concentrate prepared in our environment with a view to improving the quality of services available, consequently this study was carried out. Fifty platelet concentrates were assessed for pH, swirling index, volume, platelet count, WBC count and red cell count. All the concentrate preparations were within acceptable pH value of 7.25. The average volume was 18.52 mls/bag. The average platelet count per concentrate was 41.7+/-39.5 x 10(9)/L. Thirty-five percent (35%) of the platelet concentrates had a value > 55 x 10(9)/L. White blood cell count (WBC) < 12 x 10(9)/L was seen 49% of the platelet concentrates prepared. Forty percent (40%) of the platelet concentrate had a red blood cell count (RBC count) > 12 x 10(9)/L with 30% not having red cell contamination. Swirling test was positive in 72% of the platelet concentrate units. The results from this study point to the need to improve the quality of the platelet concentrates being prepared in our blood bank in order to get maximum therapeutic values. There is also a need for regular quality control of the platelet concentrate being prepared in our blood bank.
由于尼日利亚伊巴丹大学学院医院（U.C.H.）患者护理水平的提高以及与骨髓再生障碍相关的强化治疗方案的使用，血小板输注的需求有所增加。因此，有必要评估我们环境中制备的血小板浓缩物的质量，以提高现有服务的质量，为此开展了本研究。对50份血小板浓缩物进行了pH值、漩涡指数、体积、血小板计数、白细胞计数和红细胞计数的评估。所有浓缩物制剂的pH值均在可接受的7.25范围内。平均体积为18.52毫升/袋。每份浓缩物的平均血小板计数为41.7±39.5×10⁹/L。35%的血小板浓缩物的值>55×10⁹/L。在制备的血小板浓缩物中，49%的白细胞计数（WBC）<12×10⁹/L。40%的血小板浓缩物红细胞计数（RBC计数）>12×10⁹/L，30%没有红细胞污染。72%的血小板浓缩物单位漩涡试验呈阳性。本研究结果表明，有必要提高我们血库中制备的血小板浓缩物的质量，以获得最大治疗价值。还需要对我们血库中制备的血小板浓缩物进行定期质量控制。
