Gikas Aristofanis, Sotiropoulos Alexios, Panagiotakos Demosthenes, Peppas Theodoros, Skliros Eystathios, Pappas Stavros
Health Centre of Salamis, Salamis, Greece.
BMC Public Health. 2004 Feb 14;4:2. doi: 10.1186/1471-2458-4-2.
The continuous monitoring and future prediction of the growing epidemic of diabetes mellitus worldwide presuppose consistent information about the extent of the problem. The aim of this study was to determine the prevalence of diagnosed diabetes and to identify associated risk factors in a sample of adult urban Greek population.
A cross-sectional population-based survey was conducted in municipality of Salamis, Greece, during an election day (2002). The study sample consisted of 2805 participants, aged 20-94 years. Data were collected using a standardized short questionnaire that was completed by a face-to-face interview. Multiple regression analyses were performed to evaluate the association of diabetes with potential risk factors.
The overall prevalence of diagnosed diabetes was 8.7% (95% CI 7.7-9.8%). After age adjustment for the current adult population (2001 census) of Greece, the projection prevalence was calculated to 8.2%. Multivariate logistic regression analysis identified as independent risk factors: increasing age (odds ratio, OR = 1.07, 95% CI 1.06-1.08), male sex (OR = 1.43, 95% CI 1.04-1.95), overweight and obesity (OR = 1.97, 95% CI 1.29-3.01 and OR = 3.76, 95% CI 2.41-5.86, respectively), family history of diabetes (OR = 6.91, 95% CI 5.11-9.34), hypertension (OR = 2.19, 95% CI 1.60-2.99) and, among women, lower educational level (OR = 2.62, 95% CI 1.22-5.63). The prevalence of overweight and obesity, based on self-reported BMI, were 44.2% and 18.4%, respectively. Moreover, the odds for diabetes in obese subjects with family history were 25-fold higher than those with normal weight and without family history of diabetes, while the odds in overweight subjects with family history of diabetes were 15-fold higher.
Our findings indicated that the prevalence of diabetes is high in Greek population. It is suggested that the main modifiable contributing factor is obesity, whose effect is extremely increased upon positive heredity presence.
对全球糖尿病疫情不断加剧的持续监测和未来预测,是以关于该问题严重程度的一致信息为前提的。本研究的目的是确定希腊成年城市人口样本中已确诊糖尿病的患病率,并识别相关风险因素。
在希腊萨拉米斯市的一个选举日(2002年)进行了一项基于人群的横断面调查。研究样本包括2805名年龄在20 - 94岁之间的参与者。通过面对面访谈使用标准化简短问卷收集数据。进行多元回归分析以评估糖尿病与潜在风险因素之间的关联。
已确诊糖尿病的总体患病率为8.7%(95%可信区间7.7 - 9.8%)。根据希腊当前成年人口(2001年人口普查)进行年龄调整后,预计患病率计算为8.2%。多因素逻辑回归分析确定的独立风险因素为:年龄增长(比值比,OR = 1.07,95%可信区间1.06 - 1.08)、男性(OR = 1.43,95%可信区间1.04 - 1.95)、超重和肥胖(OR分别为1.97,95%可信区间1.29 - 3.01和3.76,95%可信区间2.41 - 5.86)、糖尿病家族史(OR = 6.91,95%可信区间5.11 - 9.34)、高血压(OR = 2.19,95%可信区间1.60 - 2.99)以及在女性中,较低的教育水平(OR = 2.62,95%可信区间1.22 - 5.63)。根据自我报告的体重指数,超重和肥胖的患病率分别为44.2%和18.4%。此外,有家族史的肥胖受试者患糖尿病的几率比体重正常且无糖尿病家族史的受试者高25倍,而有糖尿病家族史的超重受试者患糖尿病的几率高15倍。
我们的研究结果表明希腊人群中糖尿病患病率很高。提示主要的可改变促成因素是肥胖,在存在阳性遗传因素时其影响会极大增加。