Beydoun Hind, Itani Mohammad, Tamim Hala, Aaraj Alia, Khogali Mustafa, Yunis Khalid
Department of Pediatrics, American University of Beirut Medical Center, Beirut, Lebanon.
J Perinatol. 2004 Apr;24(4):228-35. doi: 10.1038/sj.jp.7211064.
To analyze the impact of maternal age at first childbirth on the incidence of preterm delivery and low birthweight among single live births delivered to nulliparous Lebanese women in Greater Beirut.
Eligible subjects were selected from a consecutive sample of neonatal admissions to nine National Collaborative Perinatal Network participating hospitals over a three-year period (April 1, 1999 to March 31, 2002). Chi-square tests and logistic regression analyses were applied.
Out of 5556 nulliparous mothers, 5.4% had a preterm delivery and 5.2% a low-birthweight infant. In the multivariate analysis, preterm delivery was not significantly affected by old maternal age. Mothers aged 25 years or more remained a high-risk group for low birthweight even after controlling for potentially confounding characteristics.
Maternal age at first childbirth above 25 years is an independent risk factor for low birthweight, but not for preterm delivery, an outcome influenced mainly by obstetric complications.
分析首次分娩时母亲年龄对大贝鲁特地区黎巴嫩未生育妇女单胎活产中早产和低出生体重发生率的影响。
符合条件的研究对象选自九家参与全国围产期协作网络的医院在三年期间（1999年4月1日至2002年3月31日）连续收治的新生儿。采用卡方检验和逻辑回归分析。
在5556名未生育母亲中，5.4%发生了早产，5.2%产下了低出生体重儿。在多变量分析中，母亲年龄较大对早产无显著影响。即使在控制了潜在的混杂特征后，25岁及以上的母亲仍是低出生体重的高危人群。
首次分娩时母亲年龄超过25岁是低出生体重的独立危险因素，但不是早产的危险因素，早产主要受产科并发症影响。
