Bocio Ana, Llobet Juan M, Domingo Jose L
Laboratory of Toxicology and Environmental Health, School of Medicine, "Rovira i Virgili" University, San Lorenzo 21, 43201 Reus, Spain.
J Agric Food Chem. 2004 Mar 24;52(6):1769-72. doi: 10.1021/jf0352172.
Although polychlorinated diphenyl ethers (PCDEs) are recognized environmental pollutants, information concerning human exposure to these organic substances is very scarce. For the present study the concentrations of PCDEs in a number of foodstuffs acquired in Catalonia, Spain, were determined. The dietary intake of PCDEs was estimated for various age groups of the general population living in this Spanish region. With the exception of fish and shellfish, PCDE concentrations were under the limit of detection in the 10 remaining food groups analyzed. For an adult (20-65 years old) male of 70 kg average body weight, the estimated total dietary intake of PCDEs was 41 ng/day. It was assumed that if a PCDE congener was below the detection limit, the concentration was equal to half of the limit of detection. The highest exposure to PCDEs through the diet corresponded to the group aged 51-65 years, whereas the lowest intake corresponded to the youngest group (4-9 years). With the exception of the group aged >65 years, PCDE intake was always higher in males than in females. The results of this study should be of interest for future assessments of time trends in human exposure to PCDEs through the diet.
尽管多氯二苯醚（PCDEs）被公认为环境污染物，但有关人类接触这些有机物质的信息却非常匮乏。在本研究中，测定了西班牙加泰罗尼亚地区采集的多种食品中PCDEs的浓度。估算了居住在该西班牙地区的不同年龄组普通人群的PCDEs膳食摄入量。除鱼类和贝类外，在所分析的其余10类食物中，PCDEs浓度均低于检测限。对于一名平均体重70千克的成年男性（20 - 65岁），估计PCDEs的总膳食摄入量为41纳克/天。假定如果一种PCDE同系物低于检测限，则其浓度等于检测限的一半。通过饮食接触PCDEs最多的是51 - 65岁年龄组，而摄入量最低的是最年轻的组（4 - 9岁）。除65岁以上年龄组外，男性的PCDEs摄入量总是高于女性。本研究结果对于未来评估人类通过饮食接触PCDEs的时间趋势应具有参考价值。
