Wille A C M, Oliveira F A, Soares M A M, Gomes J R
Departamento de Biologia Estrutural, Molecular e Genética, Setor de Ciências Biológicas e da Saúde, Universidade Estadual de Ponta Grossa, Paraná, Brazil.
Cell Prolif. 2004 Apr;37(2):189-94. doi: 10.1111/j.1365-2184.2004.00295.x.
Cell cycle time (T(C)) and the rate of entry of cells into mitosis (r(M)) in the jejunum and duodenum of young rats were investigated using the stathmokinetic method. The cell cycle times in the jejunum were 24.3 and 28.3 h in light and dark periods, respectively. Cell cycle times in the duodenum were 17.1 and 21.5 h in light and dark periods, respectively. Rates of entry of cells into mitosis in the jejunum were 1.2 and 1.1 cells/cell/h in light and dark periods and rates of entry of cells into mitosis in the duodenum were 1.4 and 1.8 cells/cell/h in light and dark periods, respectively. Although these changes to cell cycle time values are not statistically significant, the variation between the two periods should be considered in relation to its possible biological effects.
采用静止期动力学方法研究了幼鼠空肠和十二指肠的细胞周期时间(T(C))以及细胞进入有丝分裂的速率(r(M))。空肠在光照期和黑暗期的细胞周期时间分别为24.3小时和28.3小时。十二指肠在光照期和黑暗期的细胞周期时间分别为17.1小时和21.5小时。空肠在光照期和黑暗期细胞进入有丝分裂的速率分别为1.2个细胞/细胞/小时和1.1个细胞/细胞/小时,十二指肠在光照期和黑暗期细胞进入有丝分裂的速率分别为1.4个细胞/细胞/小时和1.8个细胞/细胞/小时。虽然这些细胞周期时间值的变化没有统计学意义,但应考虑两个时期之间的差异及其可能的生物学效应。