Exploring the phosphoproteome with mass spectrometry.
作者信息
Peters Eric C, Brock Ansgar, Ficarro Scott B
机构信息
Genomics Institute of the Novartis Research Foundation, 10675 John Jay Hopkins Drive, San Diego, CA 92121, USA.
出版信息
Mini Rev Med Chem. 2004 Mar;4(3):313-24. doi: 10.2174/1389557043487330.
PMID:15032677
Abstract
Protein phosphorylation is a reversible post-translational modification crucial in the control of numerous regulatory pathways. Understanding the highly interconnected nature of such networks requires new broader-scale analysis techniques. This report summarizes recent advances in the use of mass spectrometry to assess phosphorylation events in ever more complex systems.
摘要
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