Mumby Marc, Brekken Deirdre
Department of Pharmacology and the Alliance for Cellular Signaling, University of Texas Southwestern Medical Center, Dallas, TX 75390-9041, USA.
Genome Biol. 2005;6(9):230. doi: 10.1186/gb-2005-6-9-230. Epub 2005 Aug 17.
Developments in the field of phosphoproteomics have been fueled by the need simultaneously to monitor many different phosphoproteins within the signaling networks that coordinate responses to changes in the cellular environment. This article presents a brief review of phosphoproteomics with an emphasis on the biological insights that have been derived so far.
磷酸化蛋白质组学领域的发展是由在协调细胞对环境变化反应的信号网络中同时监测许多不同磷酸化蛋白质的需求所推动的。本文简要回顾了磷酸化蛋白质组学,重点介绍了迄今为止所获得的生物学见解。