Moine P, Ecoffey C
Département d'Anesthésie-Réanimation, Hôpital de Bicêtre, Le Kremlin-Bicêtre.
Ann Fr Anesth Reanim. 1992;11(2):141-4. doi: 10.1016/s0750-7658(05)80004-8.
A study of the duration of analgesia and of the respiratory response to hypercapnia was carried out in 14 children who had had a caudal block with either bupivacaine alone (group B) or combined with fentanyl (Group B+F). Fourteen ASA I or II 5 to 10-year-old children undergoing genital and urinary surgery were included. They were not premedicated. At first, general anaesthesia was induced with halothane and nitrous oxide in oxygen. Thereafter, caudal anaesthesia was then carried out with 1 ml.kg-1 of 0.25% bupivacaine with adrenaline 1 in 200,000. Group B+F patients were also given 1 microgram.kg-1 of fentanyl in 1 ml of normal saline, and those in Group B 1 ml of normal saline. The level of sensory loss on leaving the operating theatre as well as the duration of motor paralysis were monitored. Postoperative pain was scored with Hannalah and Broadman's score (0 to 10) 2, 4, 8 and 24 h after the caudal block. Respiratory rate (fR), tidal volume (VT) and minute ventilation (VE) were assessed 10 min before induction of general anaesthesia, and 30, 60 and 120 min after the caudal anaesthesia. Petco2 was also measured before induction of general anaesthesia, and 60 and 120 min after caudal anaesthesia; at the same times, the ventilatory response to hypercapnia was assessed using Read's method with a Douglas bag containing 7% CO2 and 93% O2.(ABSTRACT TRUNCATED AT 250 WORDS)
对14名接受骶管阻滞的儿童进行了镇痛持续时间和对高碳酸血症呼吸反应的研究。这些儿童分别单独使用布比卡因(B组)或联合芬太尼(B + F组)进行骶管阻滞。纳入了14名年龄在5至10岁、ASA I或II级、接受生殖泌尿系统手术的儿童,且未进行术前用药。首先,用氟烷和氧化亚氮 - 氧气诱导全身麻醉。之后,用1 ml.kg-1的0.25%布比卡因加1:200,000肾上腺素进行骶管麻醉。B + F组患者还在1 ml生理盐水中给予1微克.kg-1的芬太尼,B组患者给予1 ml生理盐水。监测离开手术室时的感觉丧失水平以及运动麻痹的持续时间。在骶管阻滞后2、4、8和24小时,用汉纳拉和布罗德曼评分(0至10分)对术后疼痛进行评分。在全身麻醉诱导前10分钟以及骶管麻醉后30、60和120分钟评估呼吸频率(fR)、潮气量(VT)和分钟通气量(VE)。在全身麻醉诱导前以及骶管麻醉后60和120分钟测量呼气末二氧化碳分压(Petco2);同时,使用装有7%二氧化碳和93%氧气的道格拉斯袋,采用里德方法评估对高碳酸血症的通气反应。(摘要截断于250字)