• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

不断缩小的基因组学

Shrinking genomics.

作者信息

Thomson Nicholas R, Sebaihia Mohammed, Cerdeño-Tárraga Ana M, Holden Matthew T, Parkhill Julian

机构信息

Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK.

出版信息

Nat Rev Microbiol. 2004 Jan;2(1):11. doi: 10.1038/nrmicro800.

DOI:10.1038/nrmicro800
PMID:15035003
Abstract

Two bacteria are featured this month, and both are at the lower end of the genome size scale. The first, Mycoplasma gallisepticum, belongs to a group of bacteria that have been studied both as important human and animal pathogens and in the pursuit of understanding the essential functions of a self-replicating minimal cell. The second, Nanoarchaeum equitans, is an obligate symbiont that only grows in co-culture with another archaeon. N. equitans seems to be the coelacanth of the microbial world--it has been assigned to a new phylum and represents a primitive form of prokaroytic life.

摘要

本月介绍了两种细菌,它们的基因组大小均处于较低水平。第一种是鸡毒支原体,它属于一类细菌,这类细菌既作为重要的人类和动物病原体被研究,也用于探索自我复制的最小细胞的基本功能。第二种是嗜热栖热菌,它是一种专性共生菌,仅在与另一种古生菌共培养时才能生长。嗜热栖热菌似乎是微生物世界中的腔棘鱼——它被归为一个新的门,代表了原核生物生命的一种原始形式。

相似文献

1
Shrinking genomics.不断缩小的基因组学
Nat Rev Microbiol. 2004 Jan;2(1):11. doi: 10.1038/nrmicro800.
2
Persistence of Mycoplasma gallisepticum in chickens after treatment with enrofloxacin without development of resistance.鸡经恩诺沙星治疗后鸡毒支原体的持续存在且未产生耐药性。
Vet Microbiol. 2005 Mar 20;106(1-2):129-37. doi: 10.1016/j.vetmic.2004.11.016. Epub 2005 Jan 24.
3
Identification of a virulence-associated determinant, dihydrolipoamide dehydrogenase (lpd), in Mycoplasma gallisepticum through in vivo screening of transposon mutants.通过转座子突变体的体内筛选鉴定鸡毒支原体中与毒力相关的决定因素二氢硫辛酰胺脱氢酶(lpd)。
Infect Immun. 2006 Feb;74(2):931-9. doi: 10.1128/IAI.74.2.931-939.2006.
4
The tree of life might be rooted in the branch leading to Nanoarchaeota.生命之树可能根植于通往纳古菌门的分支中。
Gene. 2007 Oct 15;401(1-2):108-13. doi: 10.1016/j.gene.2007.07.004. Epub 2007 Jul 17.
5
All things great and small.事无巨细。
Trends Microbiol. 2004 Jan;12(1):7-8. doi: 10.1016/j.tim.2003.11.009.
6
Robust determinants of thermostability highlighted by a codon frequency index capable of discriminating thermophilic from mesophilic genomes.通过能够区分嗜热菌和嗜温菌基因组的密码子频率指数突出显示的热稳定性的强大决定因素。
J Proteome Res. 2007 Jul;6(7):2502-8. doi: 10.1021/pr060670p. Epub 2007 May 26.
7
Strain differentiating real-time PCR for Mycoplasma gallisepticum live vaccine evaluation studies.用于鸡毒支原体活疫苗评估研究的菌株鉴别实时荧光定量PCR
Vet Microbiol. 2008 May 25;129(1-2):179-87. doi: 10.1016/j.vetmic.2007.11.017. Epub 2007 Nov 22.
8
Molecular characterization and determination of antimicrobial resistance of Mycoplasma gallisepticum isolated from chickens.从鸡中分离出的鸡毒支原体的分子特征及抗菌药物耐药性测定
Vet Microbiol. 2007 Nov 15;125(1-2):59-65. doi: 10.1016/j.vetmic.2007.05.011. Epub 2007 May 18.
9
Metabolite profiling of Mycoplasma gallisepticum mutants, combined with bioinformatic analysis, can reveal the likely functions of virulence-associated genes.鸡毒支原体突变株的代谢组学分析,结合生物信息学分析,可以揭示与毒力相关基因的可能功能。
Vet Microbiol. 2018 Sep;223:160-167. doi: 10.1016/j.vetmic.2018.08.001. Epub 2018 Aug 2.
10
A recombinant PvpA protein-based diagnostic prototype for rapid screening of chicken Mycoplasma gallisepticum infections.一种基于重组PvpA蛋白的诊断原型,用于快速筛查鸡败血支原体感染。
Vet Microbiol. 2008 May 25;129(1-2):139-49. doi: 10.1016/j.vetmic.2007.11.028. Epub 2007 Dec 4.

引用本文的文献

1
Cooperation and Competition Were Primary Driving Forces for Biological Evolution.合作与竞争是生物进化的主要驱动力。
Microb Physiol. 2025;35(1):13-29. doi: 10.1159/000544890. Epub 2025 Feb 25.