Chaudhari M, Balmer C, Heng J T, Wright J, Stümper O
The Heart Unit, Birmingham Children's Hospital--NHS Trust, Steelhouse Lane, Birmingham, UK.
Eur J Echocardiogr. 2004 Mar;5(2):111-7. doi: 10.1016/S1525-2167(03)00052-0.
To assess the utility of continuous wave Doppler evaluation of velocity profiles across a Blalock-Taussig (BT) shunt in the evaluation of pulmonary artery pressure and pulmonary blood flow.
Eleven children with complex congenital heart disease with a BT shunt as the sole source of pulmonary blood supply were studied prospectively (median age 5 (0.3-21) months). Doppler evaluations of shunt flow velocity profile and cardiac catheterization were carried out simultaneously. Pulmonary artery pressure and flow were estimated using the modified Bernoulli equation and velocity time integral of shunt flow. There was a positive correlation between (1) the Doppler estimates for mean pulmonary artery pressure, using the diastolic flow velocity, and the mean pulmonary venous wedge pressure ( r = 0.93, SEE = 1.0 mmHG; P<0.001 ) and (2) the Doppler derived and calculated pulmonary blood flow ( r = 0.9, SEE = 0.19 l/min; P<0.001). In contrast, the Doppler estimates for mean pulmonary artery pressure using the peak or mean Doppler gradients were poor.
The diastolic BT shunt flow velocity can be used reliably to predict mean pulmonary artery pressure when a BT shunt is the sole source of pulmonary artery flow. There was agreement between Doppler predicted pulmonary blood flow and catheter based calculations. These findings may prove a useful tool for perioperative management.
评估通过连续波多普勒评估布莱洛克 - 陶西格(BT)分流处的速度剖面在评估肺动脉压力和肺血流量方面的效用。
对11例患有复杂先天性心脏病且以BT分流作为肺血流唯一来源的儿童进行前瞻性研究(中位年龄5(0.3 - 21)个月)。同时进行分流血流速度剖面的多普勒评估和心导管检查。使用改良的伯努利方程和分流血流的速度时间积分来估计肺动脉压力和流量。(1)使用舒张期血流速度的多普勒估计平均肺动脉压力与平均肺静脉楔压之间存在正相关(r = 0.93,标准误 = 1.0 mmHg;P < 0.001),(2)多普勒得出的和计算出的肺血流量之间存在正相关(r = 0.9,标准误 = 0.19 l/min;P < 0.001)。相比之下,使用峰值或平均多普勒梯度的多普勒估计平均肺动脉压力的效果较差。
当BT分流是肺动脉血流的唯一来源时,舒张期BT分流血流速度可可靠地用于预测平均肺动脉压力。多普勒预测的肺血流量与基于导管的计算结果一致。这些发现可能为围手术期管理提供有用的工具。