Arnaz Ahmet, Pişkin Şenol, Oğuz Gökçe Nur, Yalçınbaş Yusuf, Pekkan Kerem, Sarıoğlu Tayyar
Department of Cardiovascular Surgery, Faculty of Medicine, Acıbadem Mehmet Ali Aydınlar University; İstanbul-Turkey.
Anatol J Cardiol. 2018 Jul;20(1):2-8. doi: 10.14744/AnatolJCardiol.2018.54810.
This study aimed to identify the best graft-to-pulmonary artery (PA) anastomosis angle measuring pulmonary blood flow, wall shear stress (WSS), and shunt flow.
A tetralogy of Fallot with pulmonary atresia computer model was used to study three different modified Blalock-Taussig shunt (mBTS) anastomosis angle configurations with three different PA diameter configurations. Velocity and WSS were analyzed, and the flow rates at the right PA (RPA) and left PA (LPA) were calculated.
A 4-mm and 8-mm diameter of RPA and LPA, respectively with vertical shunt angle produces the highest total flow. In the RPA larger diameter than the LPA configutations, the left-leaning shunt produces the lowest total PA flow whereas in the LPA larger diameter than the RPA configuratios, the right-leaning shunt produces the lowest total PA flow. Therefore, the shunt anastomosis should not be leaned through the narrow side of PA to reach best flow. As the flow inside the shunt increased, WSS also increased due to enhanced velocity gradients.
The anastomosis angle between the conduit and PA affects the flow to PA. Vertical anastomosis configurations increase the total PA flow; thus, these configurations are preferable than the leaned configurations.
本研究旨在确定测量肺血流量、壁面剪应力(WSS)和分流流量时,移植物与肺动脉(PA)的最佳吻合角度。
采用法洛四联症合并肺动脉闭锁计算机模型,研究三种不同改良布莱洛克-陶西格分流术(mBTS)吻合角度配置与三种不同PA直径配置。分析流速和WSS,并计算右肺动脉(RPA)和左肺动脉(LPA)的流量。
RPA和LPA直径分别为4mm和8mm,垂直分流角度时总流量最高。在RPA直径大于LPA的配置中,向左倾斜的分流产生的总PA流量最低,而在LPA直径大于RPA的配置中,向右倾斜的分流产生的总PA流量最低。因此,分流吻合不应通过PA的狭窄侧倾斜以达到最佳流量。随着分流内流量增加,由于速度梯度增强,WSS也增加。
管道与PA之间的吻合角度影响流向PA的流量。垂直吻合配置增加了总PA流量;因此,这些配置比倾斜配置更可取。