Mayer-Scholl Anne, Averhoff Petra, Zychlinsky Arturo
Department for Cellular Microbiology, Max-Planck Institute for Infection Biology, Schumannstr. 21/22, 10117 Berlin, Germany.
Curr Opin Microbiol. 2004 Feb;7(1):62-6. doi: 10.1016/j.mib.2003.12.004.
Many pathogens can manipulate macrophages after phagocytosis yet are efficiently killed by neutrophils. This poses the question of whether neutrophils have mechanisms that enable them to specifically recognise pathogens and have pathogens evolved mechanisms to modulate neutrophil function? Here, we review recent work on neutrophils and their interaction with four different bacteria: Staphylococcus aureus, Helicobacter pylori, Anaplasma phagocytophilum and members of the Enterobacteriae family.
许多病原体在被吞噬后能够操纵巨噬细胞，但却能被中性粒细胞有效杀灭。这就提出了一个问题，即中性粒细胞是否具有使其能够特异性识别病原体的机制，以及病原体是否进化出了调节中性粒细胞功能的机制？在这里，我们综述了关于中性粒细胞及其与四种不同细菌相互作用的最新研究：金黄色葡萄球菌、幽门螺杆菌、嗜吞噬细胞无形体和肠杆菌科成员。
