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微生物表面活性剂在生物医学科学中的潜在应用。

Potential applications of microbial surfactants in biomedical sciences.

作者信息

Singh Pooja, Cameotra Swaranjit Singh

机构信息

Institute of Microbial Technology, Sector 39 A, Chandigarh 160036, India.

出版信息

Trends Biotechnol. 2004 Mar;22(3):142-6. doi: 10.1016/j.tibtech.2004.01.010.

DOI:10.1016/j.tibtech.2004.01.010
PMID:15036865
Abstract

The main commercial use of biosurfactants is in pollution remediation because of their ability to stabilize emulsions. This enhances the solubility and availability of hydrophobic pollutants, thus increasing their potential for biodegradation. One useful property of many biosurfactants that has not been reviewed extensively is their antimicrobial activity. Several biosurfactants have strong antibacterial, antifungal and antiviral activity. Other medically relevant uses of biosurfactants include their role as anti-adhesive agents to pathogens, making them useful for treating many diseases and as therapeutic and probiotic agents. Here, we discuss some of the new and exciting applications and related developments of various microbial surfactants in the field of biomedical sciences.

摘要

生物表面活性剂的主要商业用途是污染修复,因为它们具有稳定乳液的能力。这提高了疏水性污染物的溶解度和可利用性,从而增加了它们被生物降解的可能性。许多生物表面活性剂的一个尚未得到广泛综述的有用特性是它们的抗菌活性。几种生物表面活性剂具有很强的抗菌、抗真菌和抗病毒活性。生物表面活性剂在医学上的其他相关用途包括它们作为病原体抗黏附剂的作用,这使它们可用于治疗多种疾病,以及作为治疗剂和益生菌剂。在此,我们讨论各种微生物表面活性剂在生物医学科学领域的一些新的、令人兴奋的应用及相关进展。

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1
Potential applications of microbial surfactants in biomedical sciences.微生物表面活性剂在生物医学科学中的潜在应用。
Trends Biotechnol. 2004 Mar;22(3):142-6. doi: 10.1016/j.tibtech.2004.01.010.
2
Biosurfactants: potential applications in medicine.生物表面活性剂:在医学中的潜在应用。
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Recent applications of biosurfactants as biological and immunological molecules.生物表面活性剂作为生物和免疫分子的最新应用。
Curr Opin Microbiol. 2004 Jun;7(3):262-6. doi: 10.1016/j.mib.2004.04.006.
4
Biomedical and therapeutic applications of biosurfactants.生物表面活性剂在生物医药和治疗中的应用。
Adv Exp Med Biol. 2010;672:75-87. doi: 10.1007/978-1-4419-5979-9_6.
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Environmental applications for biosurfactants.生物表面活性剂的环境应用。
Environ Pollut. 2005 Jan;133(2):183-98. doi: 10.1016/j.envpol.2004.06.009.
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Biofilm inhibition and antimicrobial action of lipopeptide biosurfactant produced by heavy metal tolerant strain Bacillus cereus NK1.耐重金属芽孢杆菌 NK1 所产脂肽生物表面活性剂的抑菌和抗菌作用
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Potential therapeutic applications of biosurfactants.生物表面活性剂的潜在治疗应用。
Trends Pharmacol Sci. 2013 Dec;34(12):667-75. doi: 10.1016/j.tips.2013.10.002. Epub 2013 Oct 29.

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