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皮肤血管瘤:相关肝血管瘤的患病率及超声特征

Cutaneous haemangioma: prevalence and sonographic characteristics of associated hepatic haemangioma.

作者信息

Hughes J A, Hill V, Patel K, Syed S, Harper J, De Bruyn R

机构信息

Radiology Department, Great Ormond Street Hospital for Children, Great Ormond Street, London, UK.

出版信息

Clin Radiol. 2004 Mar;59(3):273-80. doi: 10.1016/S0009-9260(03)00267-8.

Abstract

AIMS

To determine the prevalence of hepatic haemangiomas (HH) occurring with multiple or large cutaneous haemangiomas (CH), and compare the ultrasound (US) characteristics of HH with morphology of concurrent CH.

MATERIALS AND METHODS

Retrospective and prospective sonographic and clinical analysis was undertaken on 69 patients referred for US to exclude silent HH. This comprised 62 patients referred over 6 years with six or more CH or one large CH (#10878;5 cm) and seven patients referred over 1 year with three to five small CH.

RESULTS

HH occurred in 45% miliary CH and 40% mixed small and large CH, but also in 12-14% of patients with one large or three or more small CH. None had HH progression. There was association between HH sonographic characteristics and CH number and morphology.

CONCLUSION

Clinically silent HH occurred in nearly one in four of infants presenting overall with six or more small CH or large CH. Previous studies have documented HH mortality between 18 and 80%, although this was not shown in our study. Therefore, if clinical suspicion exists, US is indicated to enable early steroid treatment if significant HH are present.

摘要

目的

确定多发性或大型皮肤血管瘤(CH)患者中肝血管瘤(HH)的患病率,并比较HH的超声(US)特征与同时存在的CH的形态。

材料与方法

对69例因超声检查以排除隐匿性HH而转诊的患者进行回顾性和前瞻性超声及临床分析。其中包括62例在6年期间转诊的患者,这些患者有6个或更多的CH或1个大型CH(≥5 cm),以及7例在1年期间转诊的患者,这些患者有3至5个小型CH。

结果

HH出现在45%的粟粒性CH患者和40%的大小混合型CH患者中,但在有1个大型CH或3个或更多小型CH的患者中也有12% - 14%出现HH。无一例HH有进展。HH的超声特征与CH的数量和形态之间存在关联。

结论

在总体上有6个或更多小型CH或大型CH的婴儿中,近四分之一存在临床隐匿性HH。既往研究记录的HH死亡率在18%至80%之间,尽管本研究未显示这一点。因此,如果存在临床怀疑,应进行超声检查,以便在存在显著HH时能够早期使用类固醇治疗。

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