Suyama Mikita, Torrents David, Bork Peer
Biocomputing, European Molecular Biology Laboratory, Meyerhofstrasse 1, D-69012 Heidelberg, Germany.
Bioinformatics. 2004 Aug 12;20(12):1968-70. doi: 10.1093/bioinformatics/bth172. Epub 2004 Mar 22.
BLAST2GENE is a program that allows a detailed analysis of genomic regions containing completely or partially duplicated genes. From a BLAST (or BL2SEQ) comparison of a protein or nucleotide query sequence with any genomic region of interest, BLAST2GENE processes all high scoring pairwise alignments (HSPs) and provides the disposition of all independent copies along the genomic fragment. The results are provided in text and PostScript formats to allow an automatic and visual evaluation of the respective region.
The program is available upon request from the authors. A web server of BLAST2GENE is maintained at http://www.bork.embl.de/blast2gene
BLAST2GENE是一个程序,可用于对包含完全或部分重复基因的基因组区域进行详细分析。通过将蛋白质或核苷酸查询序列与任何感兴趣的基因组区域进行BLAST(或BL2SEQ)比较,BLAST2GENE会处理所有高分双序列比对(HSP),并给出沿基因组片段的所有独立拷贝的分布情况。结果以文本和PostScript格式提供,以便对相应区域进行自动和可视化评估。
可向作者索取该程序。BLAST2GENE的网络服务器位于http://www.bork.embl.de/blast2gene