Yagi Takakaza, Kawakami Masayoshi, Takada Kenji
Department of Orthodontics, Graduate School of Dentistry, Osaka University, Osaka, Japan.
Angle Orthod. 2004 Feb;74(1):125-31. doi: 10.1043/0003-3219(2004)074<0125:SOCOAW>2.0.CO;2.
A male (30 years five months) who complained of mandibular prominence and masticatory dysfunction was diagnosed as a mandibular prognathic with acromegaly after cephalometric and endocrine examinations. The level of growth hormone (GH) subsequent to a transsphenoidal hypophysectomy had been controlled by medicines for about five years. Surgical orthodontic correction improved his occlusion and profile, but magnetic resonance imaging detected a recurrent adenoma in the cranial base during the retention period. The recurrence resulted in slight prognathic changes of the patient with a high level of GH. This is a case report of the treatment of an acromegalic patient discussing growth considerations that could influence the orthodontic treatment plan and long-term stability.
一名30岁零5个月的男性，因下颌前突和咀嚼功能障碍前来就诊，经头颅测量和内分泌检查后，被诊断为下颌前突伴肢端肥大症。经蝶窦垂体切除术后，生长激素（GH）水平通过药物控制了约五年。外科正畸矫正改善了他的咬合和面部轮廓，但在保持期磁共振成像检测到颅底有复发性腺瘤。复发导致患者GH水平升高，出现轻微的前突变化。这是一例肢端肥大症患者的治疗病例报告，讨论了可能影响正畸治疗计划和长期稳定性的生长因素。
