Mahandru Gireesh M, Liu Gang, Montgomery John
Department of Chemistry, Wayne State University, Detroit, Michigan 48202, USA.
J Am Chem Soc. 2004 Mar 31;126(12):3698-9. doi: 10.1021/ja049644n.
A new procedure for catalytic reductive coupling of aldehydes and alkynes has been developed. The procedure uses Ni(COD)2 with an imidazolium carbene ligand as the catalyst and triethylsilane as the reducing agent. A crossover deuterium-labeling experiment illustrated that variants involving trialkyl phosphines and imidazolium carbene ligands with a nickel catalyst proceed by different mechanisms.
一种醛与炔烃催化还原偶联的新方法已被开发出来。该方法使用带有咪唑鎓卡宾配体的Ni(COD)2作为催化剂，三乙基硅烷作为还原剂。交叉氘标记实验表明，涉及三烷基膦和带有镍催化剂的咪唑鎓卡宾配体的变体反应通过不同的机制进行。
