环孢素在免疫抑制治疗发展中的影响。
Impact of cyclosporine in the development of immunosuppressive therapy.
作者信息
Chaverri C
机构信息
Nephrology Service at The Mexico Hospital, Social Security, San Jose, Costa Rica.
出版信息
Transplant Proc. 2004 Mar;36(2 Suppl):80S-82S. doi: 10.1016/j.transproceed.2004.01.069.
Abstract
Cyclosporine has been of great interest to the transplant community during the last 20 years. It has permitted an evolution of knowledge through the changes in its original galenic formulation of Sandimmune to Neoral, and now through the recent application of the knowledge of pharmacodynamics and pharmacokinetics to tailor drug doses to each individual. The achievements of cyclosporine are still valid and possibly will be for the next years.
摘要
在过去20年里，环孢素一直备受移植界关注。它促使人们不断深入了解，从最初的山地明剂型发展到新山地明，如今又通过应用药效学和药代动力学知识为每个个体量身定制药物剂量。环孢素所取得的成果依然有效，而且在未来几年可能仍将如此。
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