Damon Henri, Dumas Pierre, Mion François
Fédération des Spécialités Digestives, Hôpital Edouard Herriot, Place d'Arsonval, 69437 Lyon Cedex.
Gastroenterol Clin Biol. 2004 Jan;28(1):16-20. doi: 10.1016/s0399-8320(04)94835-x.
To determine the impact of symptoms related to chronic constipation and fecal incontinence on quality of life.
This prospective study included 173 consecutive patients who referred addressed to our laboratory for anorectal manometry. Quality of life was evaluated using the GIQLI questionnaire, and severity of symptoms using the Cleveland Clinic scores for constipation and fecal incontinence. A correlation study was performed between the quality of life and symptoms scores.
The GIQLI questionnaire was correctly completed by 157 patients (90.7%). The mean GIQLI score was 89 +/- 24, without any significant difference between constipated and incontinent patients. The mean constipation score was 15.7/30 (range: 6-25). The mean fecal incontinence score was 10.5/20 (range: 3-16). Correlation between quality of life and symptom scores was poor. Thus, a significant threshold value for symptom scores corresponding to major alteration of quality of life could not be determined.
Quality of life is profoundly altered both in patients with chronic constipated and incontinence. Symptom scores do not allow satisfactory evaluation of the impact of chronic constipation or fecal incontinence on patients' quality of life. These results confirm the need for systematic exploration of quality of life in these patients, to correctly address the severity of functional diseases, and the influence of therapy.
确定与慢性便秘和大便失禁相关的症状对生活质量的影响。
这项前瞻性研究纳入了173例连续转诊至我们实验室进行肛门直肠测压的患者。使用胃肠道生活质量指数（GIQLI）问卷评估生活质量，使用克利夫兰诊所便秘和大便失禁评分评估症状严重程度。对生活质量和症状评分进行相关性研究。
157例患者（90.7%）正确完成了GIQLI问卷。GIQLI平均得分为89±24，便秘患者和失禁患者之间无显著差异。便秘平均评分为15.7/30（范围：6 - 25）。大便失禁平均评分为10.5/20（范围：3 - 16）。生活质量与症状评分之间的相关性较差。因此，无法确定与生活质量重大改变相对应的症状评分的显著阈值。
慢性便秘和失禁患者的生活质量均受到严重影响。症状评分无法令人满意地评估慢性便秘或大便失禁对患者生活质量的影响。这些结果证实需要对这些患者的生活质量进行系统评估，以正确评估功能性疾病的严重程度以及治疗的影响。
