Toonen H, Wolf S, Jung F, Meyer-Ebrecht D, Reim M
Lehrstuhl für Messtechnik, RWTH Aachen.
Biomed Tech (Berl). 1992 Jun;37(6):131-6. doi: 10.1515/bmte.1992.37.6.131.
Retinal hemodynamics can be quantified from videoangiographic image sequences by digital image processing. Intensity changes of dye dilution curves provide dynamics parameters of the local retinal blood flow. The measuring points of dye dilution curves have to be fixed on identical image contents in each image of a complete image sequence. To obtain measurements for every pixel on the retinal surface a motion-compensated image sequence is required. A new method adapted to the compensation of eye motion and movement artifacts in Scanning Laser Ophthalmoscopy in long image sequences (300-500 images) is presented in this paper. To inhibit error propagation of time sequential motion estimation, the eye movement is divided into two dynamic movements components. The method presented permits compensation for eye motion in retinal fluorescein angiographic sequences. Owing to the short calculation times, this algorithm can be used in clinical routine.
视网膜血流动力学可通过数字图像处理从视频血管造影图像序列中进行量化。染料稀释曲线的强度变化提供了局部视网膜血流的动力学参数。在完整图像序列的每幅图像中，染料稀释曲线的测量点必须固定在相同的图像内容上。为了获得视网膜表面每个像素的测量值，需要一个运动补偿图像序列。本文提出了一种适用于长图像序列（300 - 500幅图像）的扫描激光检眼镜中眼动和运动伪影补偿的新方法。为抑制时间序列运动估计的误差传播，将眼动分为两个动态运动分量。所提出的方法允许在视网膜荧光血管造影序列中补偿眼动。由于计算时间短，该算法可用于临床常规检查。
